Development and recent advancement in microfluidics for point of care biosensor applications: A review
Capillaries are small microscopic channels found in nature predominantly. These flow blood in animals and food, water and nutritions in plants. Mimicking these capillaries scientist discovered the micro channels and named the related study as microfluidics. These microscopic channels/capillaries hav...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Biosensors and Bioelectronics: X |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S259013702200111X |
| _version_ | 1817999874131492864 |
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| author | Praveen Lakhera Vikas Chaudhary Bhavishya Bhardwaj Parveen Kumar Sanjeev Kumar |
| author_facet | Praveen Lakhera Vikas Chaudhary Bhavishya Bhardwaj Parveen Kumar Sanjeev Kumar |
| author_sort | Praveen Lakhera |
| collection | DOAJ |
| description | Capillaries are small microscopic channels found in nature predominantly. These flow blood in animals and food, water and nutritions in plants. Mimicking these capillaries scientist discovered the micro channels and named the related study as microfluidics. These microscopic channels/capillaries have wide applications in the area of biomedical instrumentations. Microfluidics work on the combined principles of fluid dynamics, biology, chemistry, microelectronics, physics, and material science. The artificial microfluidics or capillaries can be fabricated using various techniques such as xurography, laser cutting, photolithography, injection moulding, and fast lithographic Activation of Sheets (FLASH). Capillaries have tremendous application, especially in biosensors; from sample collection to the detection of various biomolecules such as nucleic acids, proteins, carbohydrates, lipids, other metabolites, etc. This work presents a comprehensive review of the journey of capillary development, milestones achieved, and recent advancements in the area of microfluidics-based biosensors. This review is focused to meet the requirements of the researchers engaged in designing, simulating, and fabricating capillaries for the desired applications. Special insights have been given on the opportunities and challenges in capillary development. |
| first_indexed | 2024-04-14T03:14:58Z |
| format | Article |
| id | doaj.art-7716d6a4b26a473590f372b47181a36b |
| institution | Directory Open Access Journal |
| issn | 2590-1370 |
| language | English |
| last_indexed | 2024-04-14T03:14:58Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biosensors and Bioelectronics: X |
| spelling | doaj.art-7716d6a4b26a473590f372b47181a36b2022-12-22T02:15:31ZengElsevierBiosensors and Bioelectronics: X2590-13702022-09-0111100218Development and recent advancement in microfluidics for point of care biosensor applications: A reviewPraveen Lakhera0Vikas Chaudhary1Bhavishya Bhardwaj2Parveen Kumar3Sanjeev Kumar4Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, 201002, India; CSIR- Central Scientific Instruments Organization, Sector 30C, Chandigarh, 160030, IndiaAcademy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, 201002, India; CSIR- Central Scientific Instruments Organization, Sector 30C, Chandigarh, 160030, IndiaUniversity Institute of Engineering and Technology, Panjab University, Sector 14, 160064, IndiaAcademy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, 201002, India; CSIR- Central Scientific Instruments Organization, Sector 30C, Chandigarh, 160030, India; Exigo Recycling Pvt. Ltd., Noida, Uttar Pradesh, India; Corresponding author. Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, 201002, India.Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, 201002, India; CSIR- Central Scientific Instruments Organization, Sector 30C, Chandigarh, 160030, India; Corresponding author. CSIR- Central Scientific Instruments Organization, Sector 30C, Chandigarh, 160030, India.Capillaries are small microscopic channels found in nature predominantly. These flow blood in animals and food, water and nutritions in plants. Mimicking these capillaries scientist discovered the micro channels and named the related study as microfluidics. These microscopic channels/capillaries have wide applications in the area of biomedical instrumentations. Microfluidics work on the combined principles of fluid dynamics, biology, chemistry, microelectronics, physics, and material science. The artificial microfluidics or capillaries can be fabricated using various techniques such as xurography, laser cutting, photolithography, injection moulding, and fast lithographic Activation of Sheets (FLASH). Capillaries have tremendous application, especially in biosensors; from sample collection to the detection of various biomolecules such as nucleic acids, proteins, carbohydrates, lipids, other metabolites, etc. This work presents a comprehensive review of the journey of capillary development, milestones achieved, and recent advancements in the area of microfluidics-based biosensors. This review is focused to meet the requirements of the researchers engaged in designing, simulating, and fabricating capillaries for the desired applications. Special insights have been given on the opportunities and challenges in capillary development.http://www.sciencedirect.com/science/article/pii/S259013702200111XMicrofluidicsCapillaryBiosensorPoint-of-care deviceBiomedical applications |
| spellingShingle | Praveen Lakhera Vikas Chaudhary Bhavishya Bhardwaj Parveen Kumar Sanjeev Kumar Development and recent advancement in microfluidics for point of care biosensor applications: A review Biosensors and Bioelectronics: X Microfluidics Capillary Biosensor Point-of-care device Biomedical applications |
| title | Development and recent advancement in microfluidics for point of care biosensor applications: A review |
| title_full | Development and recent advancement in microfluidics for point of care biosensor applications: A review |
| title_fullStr | Development and recent advancement in microfluidics for point of care biosensor applications: A review |
| title_full_unstemmed | Development and recent advancement in microfluidics for point of care biosensor applications: A review |
| title_short | Development and recent advancement in microfluidics for point of care biosensor applications: A review |
| title_sort | development and recent advancement in microfluidics for point of care biosensor applications a review |
| topic | Microfluidics Capillary Biosensor Point-of-care device Biomedical applications |
| url | http://www.sciencedirect.com/science/article/pii/S259013702200111X |
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