Underlying mechanism and specific prevention of hemolysis-induced platelet activation
Thromboembolic complications significantly impair the outcome of hemolytic disorders. We hypothesized that red cell adenosine diphosphate (ADP) release results in significant platelet activation in hemolysis and that this prothrombotic state can be prevented by inhibition of the ADP P2Y12 receptor....
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2017-08-01
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Series: | Platelets |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/09537104.2016.1240769 |