Treatment of chronic generalized periodontitis using miramistin-containing nanomatrix as maintenance therapy: a pilot study and early results
Aim of the study was to evaluate the clinical efficacy of a nanomatrix with Miramistin based on M-Chip (Double White, Russia), which is used subgingivally as an addition to SRP (scaling and root planing) as a combination therapy in patients with chronic generalized periodontitis.Materials and method...
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| Format: | Article |
| Language: | Russian |
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LLC "Endo Press"
2020-10-01
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| Series: | Эндодонтия Today |
| Subjects: | |
| Online Access: | https://www.endodont.ru/jour/article/view/921 |
| _version_ | 1797880101905367040 |
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| author | Yu. A. Bakaev Z. S. Khabadze O. S. Mordanov Yu. A. Generalova |
| author_facet | Yu. A. Bakaev Z. S. Khabadze O. S. Mordanov Yu. A. Generalova |
| author_sort | Yu. A. Bakaev |
| collection | DOAJ |
| description | Aim of the study was to evaluate the clinical efficacy of a nanomatrix with Miramistin based on M-Chip (Double White, Russia), which is used subgingivally as an addition to SRP (scaling and root planing) as a combination therapy in patients with chronic generalized periodontitis.Materials and methods. T he s tudy i ncluded 4 5 p atients w ith c hronic g eneralized p eriodontitis (20 f emales a nd 25 males; age span is 35–60 years; mean age 57.87 ± 8.2 years). Patients with a probing depth ≥5 mm were included. Selected patients did not receive antibiotic therapy during the last 6 months of follow-up.Results. The mean clinical parameter values between the M-Chip + SRP treatment group and the SRP control group showed a statistically significant improvement in clinical parameters at 6 months compared to baseline values for the following indicators: plaque index (API), gingival pocket depth at probing, Mühlemann Bleeding Index (BI), the level of clinical attachment.Conclusions. SRP has been shown to be effective in reducing pocket depth, increasing periodontal attachment, and reducing inflammation. However, when SRP was used with the M-Chip, possible additional clinical benefits have been shown. |
| first_indexed | 2024-04-10T02:58:01Z |
| format | Article |
| id | doaj.art-77189d1a0f1246c3968d0369e13e5597 |
| institution | Directory Open Access Journal |
| issn | 1683-2981 1726-7242 |
| language | Russian |
| last_indexed | 2024-04-10T02:58:01Z |
| publishDate | 2020-10-01 |
| publisher | LLC "Endo Press" |
| record_format | Article |
| series | Эндодонтия Today |
| spelling | doaj.art-77189d1a0f1246c3968d0369e13e55972023-03-13T07:39:27ZrusLLC "Endo Press"Эндодонтия Today1683-29811726-72422020-10-01183788110.36377/1683-2981-2020-18-3-78-81884Treatment of chronic generalized periodontitis using miramistin-containing nanomatrix as maintenance therapy: a pilot study and early resultsYu. A. Bakaev0Z. S. Khabadze1O. S. Mordanov2Yu. A. Generalova3Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр стоматологии и челюстно-лицевой хирургии» Министерства здравоохранения Российской ФедерацииФедеральное государственное автономное образовательное учреждение высшего образования «Российский университет дружбы народов»Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр стоматологии и челюстно-лицевой хирургии» Министерства здравоохранения Российской ФедерацииФедеральное государственное автономное образовательное учреждение высшего образования «Российский университет дружбы народов»Aim of the study was to evaluate the clinical efficacy of a nanomatrix with Miramistin based on M-Chip (Double White, Russia), which is used subgingivally as an addition to SRP (scaling and root planing) as a combination therapy in patients with chronic generalized periodontitis.Materials and methods. T he s tudy i ncluded 4 5 p atients w ith c hronic g eneralized p eriodontitis (20 f emales a nd 25 males; age span is 35–60 years; mean age 57.87 ± 8.2 years). Patients with a probing depth ≥5 mm were included. Selected patients did not receive antibiotic therapy during the last 6 months of follow-up.Results. The mean clinical parameter values between the M-Chip + SRP treatment group and the SRP control group showed a statistically significant improvement in clinical parameters at 6 months compared to baseline values for the following indicators: plaque index (API), gingival pocket depth at probing, Mühlemann Bleeding Index (BI), the level of clinical attachment.Conclusions. SRP has been shown to be effective in reducing pocket depth, increasing periodontal attachment, and reducing inflammation. However, when SRP was used with the M-Chip, possible additional clinical benefits have been shown.https://www.endodont.ru/jour/article/view/921srpm-chipпародонтитмирамистин |
| spellingShingle | Yu. A. Bakaev Z. S. Khabadze O. S. Mordanov Yu. A. Generalova Treatment of chronic generalized periodontitis using miramistin-containing nanomatrix as maintenance therapy: a pilot study and early results Эндодонтия Today srp m-chip пародонтит мирамистин |
| title | Treatment of chronic generalized periodontitis using miramistin-containing nanomatrix as maintenance therapy: a pilot study and early results |
| title_full | Treatment of chronic generalized periodontitis using miramistin-containing nanomatrix as maintenance therapy: a pilot study and early results |
| title_fullStr | Treatment of chronic generalized periodontitis using miramistin-containing nanomatrix as maintenance therapy: a pilot study and early results |
| title_full_unstemmed | Treatment of chronic generalized periodontitis using miramistin-containing nanomatrix as maintenance therapy: a pilot study and early results |
| title_short | Treatment of chronic generalized periodontitis using miramistin-containing nanomatrix as maintenance therapy: a pilot study and early results |
| title_sort | treatment of chronic generalized periodontitis using miramistin containing nanomatrix as maintenance therapy a pilot study and early results |
| topic | srp m-chip пародонтит мирамистин |
| url | https://www.endodont.ru/jour/article/view/921 |
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