Identification and Validation of Candidate Gene Module Along With Immune Cells Infiltration Patterns in Atherosclerosis Progression to Plaque Rupture via Transcriptome Analysis

Identification and Validation of Candidate Gene Module Along With Immune Cells Infiltration Patterns in Atherosclerosis Progression to Plaque Rupture via Transcriptome Analysis

ObjectiveTo explore the differentially expressed genes (DEGs) along with infiltrating immune cells landscape and their potential mechanisms in the progression of atherosclerosis from onset to plaque rupture.MethodsIn this study, three atherosclerosis-related microarray datasets were downloaded from...

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Bibliographic Details
Main Authors: Jing Xu, Cheng Chen, Yuejin Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
atherosclerosis
plaque rupture
microarray
machine learning
immune cells
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.894879/full

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