Chemical, Metabolic, and Cellular Characterization of a FtsZ Inhibitor Effective Against Burkholderia cenocepacia

Chemical, Metabolic, and Cellular Characterization of a FtsZ Inhibitor Effective Against Burkholderia cenocepacia

There is an urgent need for new antimicrobials to treat the opportunistic Gram-negative Burkholderia cenocepacia, which represents a problematic challenge for cystic fibrosis patients. Recently, a benzothiadiazole derivative, C109, was shown to be effective against the infections caused by B. cenoce...

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Bibliographic Details
Main Authors: Laurent R. Chiarelli, Viola Camilla Scoffone, Gabriele Trespidi, Giulia Barbieri, Olga Riabova, Natalia Monakhova, Alessio Porta, Giulia Manina, Giovanna Riccardi, Vadim Makarov, Silvia Buroni
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Microbiology
Subjects:
Burkholderia cenocepacia
new antimicrobials
drug resistance
cell division
cystic fibrosis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00562/full

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