Contemporary Management of Locally Advanced and Recurrent Rectal Cancer: Views from the PelvEx Collaborative
Pelvic exenteration is a complex operation performed for locally advanced and recurrent pelvic cancers. The goal of surgery is to achieve clear margins, therefore identifying adjacent or involved organs, bone, muscle, nerves and/or vascular structures that may need resection. While these extensive r...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/14/5/1161 |
| _version_ | 1797475551020056576 |
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| author | PelvEx Collaborative |
| author_facet | PelvEx Collaborative |
| author_sort | PelvEx Collaborative |
| collection | DOAJ |
| description | Pelvic exenteration is a complex operation performed for locally advanced and recurrent pelvic cancers. The goal of surgery is to achieve clear margins, therefore identifying adjacent or involved organs, bone, muscle, nerves and/or vascular structures that may need resection. While these extensive resections are potentially curative, they can be associated with substantial morbidity. Recently, there has been a move to centralize care to specialized units, as this facilitates better multidisciplinary care input. Advancements in pelvic oncology and surgical innovation have redefined the boundaries of pelvic exenterative surgery. Combined with improved neoadjuvant therapies, advances in diagnostics, and better reconstructive techniques have provided quicker recovery and better quality of life outcomes, with improved survival This article provides highlights of the current management of advanced pelvic cancers in terms of surgical strategy and potential future developments. |
| first_indexed | 2024-03-09T20:45:43Z |
| format | Article |
| id | doaj.art-771c1f1e60ce4be8bf97582d882fd677 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-09T20:45:43Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-771c1f1e60ce4be8bf97582d882fd6772023-11-23T22:46:47ZengMDPI AGCancers2072-66942022-02-01145116110.3390/cancers14051161Contemporary Management of Locally Advanced and Recurrent Rectal Cancer: Views from the PelvEx CollaborativePelvEx CollaborativePelvic exenteration is a complex operation performed for locally advanced and recurrent pelvic cancers. The goal of surgery is to achieve clear margins, therefore identifying adjacent or involved organs, bone, muscle, nerves and/or vascular structures that may need resection. While these extensive resections are potentially curative, they can be associated with substantial morbidity. Recently, there has been a move to centralize care to specialized units, as this facilitates better multidisciplinary care input. Advancements in pelvic oncology and surgical innovation have redefined the boundaries of pelvic exenterative surgery. Combined with improved neoadjuvant therapies, advances in diagnostics, and better reconstructive techniques have provided quicker recovery and better quality of life outcomes, with improved survival This article provides highlights of the current management of advanced pelvic cancers in terms of surgical strategy and potential future developments.https://www.mdpi.com/2072-6694/14/5/1161rectal cancerlocally advanced rectal cancerrecurrent rectal cancerdiagnosticssurgical managementsurgical outcomes |
| spellingShingle | PelvEx Collaborative Contemporary Management of Locally Advanced and Recurrent Rectal Cancer: Views from the PelvEx Collaborative Cancers rectal cancer locally advanced rectal cancer recurrent rectal cancer diagnostics surgical management surgical outcomes |
| title | Contemporary Management of Locally Advanced and Recurrent Rectal Cancer: Views from the PelvEx Collaborative |
| title_full | Contemporary Management of Locally Advanced and Recurrent Rectal Cancer: Views from the PelvEx Collaborative |
| title_fullStr | Contemporary Management of Locally Advanced and Recurrent Rectal Cancer: Views from the PelvEx Collaborative |
| title_full_unstemmed | Contemporary Management of Locally Advanced and Recurrent Rectal Cancer: Views from the PelvEx Collaborative |
| title_short | Contemporary Management of Locally Advanced and Recurrent Rectal Cancer: Views from the PelvEx Collaborative |
| title_sort | contemporary management of locally advanced and recurrent rectal cancer views from the pelvex collaborative |
| topic | rectal cancer locally advanced rectal cancer recurrent rectal cancer diagnostics surgical management surgical outcomes |
| url | https://www.mdpi.com/2072-6694/14/5/1161 |
| work_keys_str_mv | AT pelvexcollaborative contemporarymanagementoflocallyadvancedandrecurrentrectalcancerviewsfromthepelvexcollaborative |