MADS-box transcription factor VdMcm1 regulates conidiation, microsclerotia formation, pathogenicity and secondary metabolism of Verticillium dahliae
Verticillium dahliae, a notorious phytopathogenic fungus, causes vascular wilt diseases in many plant species resulting in devastating yield losses worldwide. Due to its ability to colonize plant xylem and form microsclerotia, V. dahliae is highly persistent and difficult to control. In this study,...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-08-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01192/full |
| _version_ | 1828858609048485888 |
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| author | Dianguang Xiong Yonglin Wang Longyan Tian Chengming Tian |
| author_facet | Dianguang Xiong Yonglin Wang Longyan Tian Chengming Tian |
| author_sort | Dianguang Xiong |
| collection | DOAJ |
| description | Verticillium dahliae, a notorious phytopathogenic fungus, causes vascular wilt diseases in many plant species resulting in devastating yield losses worldwide. Due to its ability to colonize plant xylem and form microsclerotia, V. dahliae is highly persistent and difficult to control. In this study, we show that the MADS-box transcription factor VdMcm1 is a key regulator of conidiation, microsclerotia formation, virulence, and secondary metabolism of V. dahliae. In addition, our findings suggest that VdMcm1 is involved in cell wall integrity. Finally, comparative RNA-Seq analysis reveals 823 significantly downregulated genes in the VdMcm1 deletion mutant, with diverse biological functions in transcriptional regulation, plant infection, cell adhesion, secondary metabolism, transmembrane transport activity, and cell secretion. When taken together, these data suggest that VdMcm1 performs pleiotropic functions in V. dahliae. |
| first_indexed | 2024-12-13T02:00:03Z |
| format | Article |
| id | doaj.art-77232848140e4a3cba568fbbb769e194 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-13T02:00:03Z |
| publishDate | 2016-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-77232848140e4a3cba568fbbb769e1942022-12-22T00:03:17ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2016-08-01710.3389/fmicb.2016.01192208350MADS-box transcription factor VdMcm1 regulates conidiation, microsclerotia formation, pathogenicity and secondary metabolism of Verticillium dahliaeDianguang Xiong0Yonglin Wang1Longyan Tian2Chengming Tian3Beijing Forestry UniversityBeijing Forestry UniversityBeijing Forestry UniversityBeijing Forestry UniversityVerticillium dahliae, a notorious phytopathogenic fungus, causes vascular wilt diseases in many plant species resulting in devastating yield losses worldwide. Due to its ability to colonize plant xylem and form microsclerotia, V. dahliae is highly persistent and difficult to control. In this study, we show that the MADS-box transcription factor VdMcm1 is a key regulator of conidiation, microsclerotia formation, virulence, and secondary metabolism of V. dahliae. In addition, our findings suggest that VdMcm1 is involved in cell wall integrity. Finally, comparative RNA-Seq analysis reveals 823 significantly downregulated genes in the VdMcm1 deletion mutant, with diverse biological functions in transcriptional regulation, plant infection, cell adhesion, secondary metabolism, transmembrane transport activity, and cell secretion. When taken together, these data suggest that VdMcm1 performs pleiotropic functions in V. dahliae.http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01192/fullpathogenicitysecondary metabolismVerticillium dahliaeMicrosclerotia formationMADS-box tran |
| spellingShingle | Dianguang Xiong Yonglin Wang Longyan Tian Chengming Tian MADS-box transcription factor VdMcm1 regulates conidiation, microsclerotia formation, pathogenicity and secondary metabolism of Verticillium dahliae Frontiers in Microbiology pathogenicity secondary metabolism Verticillium dahliae Microsclerotia formation MADS-box tran |
| title | MADS-box transcription factor VdMcm1 regulates conidiation, microsclerotia formation, pathogenicity and secondary metabolism of Verticillium dahliae |
| title_full | MADS-box transcription factor VdMcm1 regulates conidiation, microsclerotia formation, pathogenicity and secondary metabolism of Verticillium dahliae |
| title_fullStr | MADS-box transcription factor VdMcm1 regulates conidiation, microsclerotia formation, pathogenicity and secondary metabolism of Verticillium dahliae |
| title_full_unstemmed | MADS-box transcription factor VdMcm1 regulates conidiation, microsclerotia formation, pathogenicity and secondary metabolism of Verticillium dahliae |
| title_short | MADS-box transcription factor VdMcm1 regulates conidiation, microsclerotia formation, pathogenicity and secondary metabolism of Verticillium dahliae |
| title_sort | mads box transcription factor vdmcm1 regulates conidiation microsclerotia formation pathogenicity and secondary metabolism of verticillium dahliae |
| topic | pathogenicity secondary metabolism Verticillium dahliae Microsclerotia formation MADS-box tran |
| url | http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01192/full |
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