Addition of Vindoline to <i>p</i>-Benzoquinone: Regiochemistry, Stereochemistry and Symmetry Considerations

Addition of Vindoline to <i>p</i>-Benzoquinone: Regiochemistry, Stereochemistry and Symmetry Considerations

Vindoline and catharanthine are the major alkaloids of <i>Catharanthus roseus</i> and are extracted in large quantities to prepare the pharmaceutically important Vinca type alkaloids vincaleukoblastine, vincristine and navelbine. The higher yield of vindoline relative to catharanthine ma...

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Bibliographic Details
Main Authors: Shamsher Ali, Eric Hénon, Ritchy Leroy, Georges Massiot
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
vindoline
benzoquinone
atropoisomerism
cytotoxicity
Online Access:https://www.mdpi.com/1420-3049/26/21/6395

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