Regulatory Status of Genome-Edited Organisms Under the Japanese Cartagena Act
The Japanese government recognizes the substantial values of genome-edited agricultural organisms and has defined in which cases these are covered by the existing regulatory framework to handle this technology. Genome-editing technologies could revolutionize and accelerate plant breeding owing to th...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-12-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fbioe.2019.00387/full |
| _version_ | 1819128917086175232 |
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| author | Mai Tsuda Mai Tsuda Kazuo N. Watanabe Kazuo N. Watanabe Ryo Ohsawa Ryo Ohsawa |
| author_facet | Mai Tsuda Mai Tsuda Kazuo N. Watanabe Kazuo N. Watanabe Ryo Ohsawa Ryo Ohsawa |
| author_sort | Mai Tsuda |
| collection | DOAJ |
| description | The Japanese government recognizes the substantial values of genome-edited agricultural organisms and has defined in which cases these are covered by the existing regulatory framework to handle this technology. Genome-editing technologies could revolutionize and accelerate plant breeding owing to the simplicity of the methods and precision of genome modifications. These technologies have spread rapidly and widely, and various genome-edited crops have been developed recently. The regulatory status of genome-edited end products is a subject of controversy worldwide. In February 2019, the Japanese government defined genome-edited end products derived by modifications of SDN-1 type (directed mutation without using a DNA sequence template) as not representing “living modified organisms” according to the Japanese Cartagena Act. Here, we describe the classification and regulatory status of genome-edited end products in this decision. We hope that reporting the progress in Japan toward the implementation of this regulatory approach will provide insight for scientific and regulatory communities worldwide. |
| first_indexed | 2024-12-22T08:35:26Z |
| format | Article |
| id | doaj.art-7726a11c35e748898f192642e7773903 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-12-22T08:35:26Z |
| publishDate | 2019-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-7726a11c35e748898f192642e77739032022-12-21T18:32:23ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852019-12-01710.3389/fbioe.2019.00387489169Regulatory Status of Genome-Edited Organisms Under the Japanese Cartagena ActMai Tsuda0Mai Tsuda1Kazuo N. Watanabe2Kazuo N. Watanabe3Ryo Ohsawa4Ryo Ohsawa5Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, JapanTsukuba Plant Innovation Research Center (T-PIRC), University of Tsukuba, Tsukuba, JapanFaculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, JapanTsukuba Plant Innovation Research Center (T-PIRC), University of Tsukuba, Tsukuba, JapanFaculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, JapanTsukuba Plant Innovation Research Center (T-PIRC), University of Tsukuba, Tsukuba, JapanThe Japanese government recognizes the substantial values of genome-edited agricultural organisms and has defined in which cases these are covered by the existing regulatory framework to handle this technology. Genome-editing technologies could revolutionize and accelerate plant breeding owing to the simplicity of the methods and precision of genome modifications. These technologies have spread rapidly and widely, and various genome-edited crops have been developed recently. The regulatory status of genome-edited end products is a subject of controversy worldwide. In February 2019, the Japanese government defined genome-edited end products derived by modifications of SDN-1 type (directed mutation without using a DNA sequence template) as not representing “living modified organisms” according to the Japanese Cartagena Act. Here, we describe the classification and regulatory status of genome-edited end products in this decision. We hope that reporting the progress in Japan toward the implementation of this regulatory approach will provide insight for scientific and regulatory communities worldwide.https://www.frontiersin.org/article/10.3389/fbioe.2019.00387/fullgenome editingregulatory statusJapanCartagena ProtocolLMOs |
| spellingShingle | Mai Tsuda Mai Tsuda Kazuo N. Watanabe Kazuo N. Watanabe Ryo Ohsawa Ryo Ohsawa Regulatory Status of Genome-Edited Organisms Under the Japanese Cartagena Act Frontiers in Bioengineering and Biotechnology genome editing regulatory status Japan Cartagena Protocol LMOs |
| title | Regulatory Status of Genome-Edited Organisms Under the Japanese Cartagena Act |
| title_full | Regulatory Status of Genome-Edited Organisms Under the Japanese Cartagena Act |
| title_fullStr | Regulatory Status of Genome-Edited Organisms Under the Japanese Cartagena Act |
| title_full_unstemmed | Regulatory Status of Genome-Edited Organisms Under the Japanese Cartagena Act |
| title_short | Regulatory Status of Genome-Edited Organisms Under the Japanese Cartagena Act |
| title_sort | regulatory status of genome edited organisms under the japanese cartagena act |
| topic | genome editing regulatory status Japan Cartagena Protocol LMOs |
| url | https://www.frontiersin.org/article/10.3389/fbioe.2019.00387/full |
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