Triple kill: DDR inhibitors, radiotherapy and immunotherapy leave cancer cells with no escape

Triple kill: DDR inhibitors, radiotherapy and immunotherapy leave cancer cells with no escape

Radiotherapy (RT) has been widely used in the clinical treatment of cancers, but radiotherapy resistance (RR) leads to RT failure, tumor recurrence and metastasis. Many studies have been performed on the potential mechanisms behind RR, and a strong link has been found between RR and DNA damage. RT-i...

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Bibliographic Details
Main Authors: Qiu Yuyue, Hu Xinru, Zeng Xiaoping, Wang Hongmei
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-10-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
radiotherapy
radioresistance
DNA damage response
immunotherapy
DDR inhibitor
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022153

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