Role of Microglial Cells in Alzheimer’s Disease Tau Propagation

Role of Microglial Cells in Alzheimer’s Disease Tau Propagation

Uncontrolled immune response in the brain contributes to the progression of all neurodegenerative disease, including Alzheimer’s disease (AD). Recent investigations have documented the prion-like features of tau protein and the involvement of microglial changes with tau pathology. While it is still...

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Bibliographic Details
Main Authors: Ena Španić, Lea Langer Horvat, Patrick R. Hof, Goran Šimić
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
blood-brain barrier
inflammation
microglia
neurodegeneration
tau protein propagation
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00271/full

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