Prevalence of resistance associated substitutions and efficacy of baseline resistance-guided chronic hepatitis C treatment in Spain from the GEHEP-004 cohort.

Prevalence of resistance associated substitutions and efficacy of baseline resistance-guided chronic hepatitis C treatment in Spain from the GEHEP-004 cohort.

Treatment guidelines differ in their recommendation to determine baseline resistance associated substitutions (RAS) before starting a first-line treatment with direct-acting antivirals (DAAs). Here we analyze the efficacy of DAA treatment with baseline RAS information. We conducted a prospective stu...

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Bibliographic Details
Main Authors: Ana Belén Pérez, Natalia Chueca, Juan Macías, Juan Antonio Pineda, Javier Salmerón, Antonio Rivero-Juárez, Carmen Hidalgo-Tenorio, María Dolores Espinosa, Francisco Téllez, Miguel Ángel Von-Wichmann, Mohamed Omar, Jesús Santos, José Hernández-Quero, José Joaquin Antón, Antonio Collado, Ana Belén Lozano, Miguel García-Deltoro, Marta Casado, Juan Manuel Pascasio, Aida Selfa, José Miguel Rosales, Alberto De la Iglesia, Juan Ignacio Arenas, Silvia García-Bujalance, María José Ríos, Enrique Bernal, Onofre Martínez, Antonio García-Herola, Mónica Vélez, Pilar Rincón, Federico García
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221231

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