Does persistence to methotrexate treatment in early rheumatoid arthritis have a familial component?

Does persistence to methotrexate treatment in early rheumatoid arthritis have a familial component?

Abstract Objectives To assess whether persistence to treatment with methotrexate (MTX) in early rheumatoid arthritis (RA) is shared among first-degree relatives with RA and to estimate any underlying heritability. Methods First-degree relative pairs diagnosed with RA 1999–2018 and starting MTX (in m...

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Bibliographic Details
Main Authors: Anton Öberg Sysojev, Thomas Frisell, Bénédicte Delcoigne, Saedis Saevarsdottir, Johan Askling, Helga Westerlind
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Methotrexate
Heritability
Familiality
Treatment persistence
Online Access:https://doi.org/10.1186/s13075-022-02873-z

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