The role of the Hippo pathway in human disease and tumorigenesis

The role of the Hippo pathway in human disease and tumorigenesis

Abstract Understanding the molecular nature of human cancer is essential to the development of effective and personalized therapies. Several different molecular signal transduction pathways drive tumorigenesis when deregulated and respond to different types of therapeutic interventions. The Hippo si...

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Bibliographic Details
Main Authors: Daniel A Barron, Jacob D Kagey
Format: Article
Language:English
Published: Wiley 2014-12-01
Series:Clinical and Translational Medicine
Subjects:
Cancer
Hippo signaling
YAP
Apoptosis
Online Access:https://doi.org/10.1186/2001-1326-3-25

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