The role of the skin microbiome in the development of alopecia areata

Human skin is a habitat to a variety of microbes that, along with their host genetic material, make up microbiome of the human skin. The composition of the microbiota in the gut and skin is influenced by many factors, such as life stage, nutrition, lifestyle and gender. Recently, there is more and m...

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Main Authors: Kinga Brzuszkiewicz, Gracjan Rudziński, Kinga Pożarowska, Arkadiusz Grunwald, Małgorzata Satora, Klaudia Piwowar, Jakub Klas
Format: Article
Language:English
Published: Kazimierz Wielki University 2022-11-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/39630
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author Kinga Brzuszkiewicz
Gracjan Rudziński
Kinga Pożarowska
Arkadiusz Grunwald
Małgorzata Satora
Klaudia Piwowar
Jakub Klas
author_facet Kinga Brzuszkiewicz
Gracjan Rudziński
Kinga Pożarowska
Arkadiusz Grunwald
Małgorzata Satora
Klaudia Piwowar
Jakub Klas
author_sort Kinga Brzuszkiewicz
collection DOAJ
description Human skin is a habitat to a variety of microbes that, along with their host genetic material, make up microbiome of the human skin. The composition of the microbiota in the gut and skin is influenced by many factors, such as life stage, nutrition, lifestyle and gender. Recently, there is more and more discussions about the increasing role of the microbiome in the development of other diseases. According to many studies, any changes in the skin microbiota are associated with the development of several dermatoses. Better understanding of the human microbiome and its interactions with the immune system could help us understand many diseases as well as could have an impact on the development of some new therapeutic methods. In this article, the current knowledge on the skin microbiome and its influence on the development of alopecia areata will be discussed. Alopecia areata (AA) is caused by an autoimmune process that destroys the hair follicles. The exact pathogenesis is unknown, but the triggering factors include: immune disorders, environmental exposures, genetic predisposition, and possibly the microbiome.
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spelling doaj.art-773bc17222404cb4a002ab671a647eb92022-12-22T02:41:40ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062022-11-01121110.12775/JEHS.2022.12.11.030The role of the skin microbiome in the development of alopecia areataKinga Brzuszkiewicz0Gracjan Rudziński1Kinga Pożarowska2Arkadiusz Grunwald3Małgorzata Satora4Klaudia Piwowar5Jakub Klas6Students’ Research Group at the Department of Toxicology, Medical University of Lublin Uniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieHuman skin is a habitat to a variety of microbes that, along with their host genetic material, make up microbiome of the human skin. The composition of the microbiota in the gut and skin is influenced by many factors, such as life stage, nutrition, lifestyle and gender. Recently, there is more and more discussions about the increasing role of the microbiome in the development of other diseases. According to many studies, any changes in the skin microbiota are associated with the development of several dermatoses. Better understanding of the human microbiome and its interactions with the immune system could help us understand many diseases as well as could have an impact on the development of some new therapeutic methods. In this article, the current knowledge on the skin microbiome and its influence on the development of alopecia areata will be discussed. Alopecia areata (AA) is caused by an autoimmune process that destroys the hair follicles. The exact pathogenesis is unknown, but the triggering factors include: immune disorders, environmental exposures, genetic predisposition, and possibly the microbiome. https://apcz.umk.pl/JEHS/article/view/39630microbiomealopeciaalopecia areataskin
spellingShingle Kinga Brzuszkiewicz
Gracjan Rudziński
Kinga Pożarowska
Arkadiusz Grunwald
Małgorzata Satora
Klaudia Piwowar
Jakub Klas
The role of the skin microbiome in the development of alopecia areata
Journal of Education, Health and Sport
microbiome
alopecia
alopecia areata
skin
title The role of the skin microbiome in the development of alopecia areata
title_full The role of the skin microbiome in the development of alopecia areata
title_fullStr The role of the skin microbiome in the development of alopecia areata
title_full_unstemmed The role of the skin microbiome in the development of alopecia areata
title_short The role of the skin microbiome in the development of alopecia areata
title_sort role of the skin microbiome in the development of alopecia areata
topic microbiome
alopecia
alopecia areata
skin
url https://apcz.umk.pl/JEHS/article/view/39630
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