Inhibition the ubiquitination of ENaC and Na,K-ATPase with erythropoietin promotes alveolar fluid clearance in sepsis-induced acute respiratory distress syndrome

Inhibition the ubiquitination of ENaC and Na,K-ATPase with erythropoietin promotes alveolar fluid clearance in sepsis-induced acute respiratory distress syndrome

Sepsis-induced acute respiratory distress syndrome (ARDS) causes significant fatalities worldwide and lacks pharmacological intervention. Alveolar fluid clearance (AFC) plays a pivotal role in the remission of ARDS and is markedly impaired in the pathogenesis of ARDS. Here, we demonstrated that eryt...

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Bibliographic Details
Main Authors: Ye Gao, Fei Cao, Xinyi Tian, Qianping Zhang, Congcong Xu, Bowen Ji, Ye-an Zhang, Linan Du, Jun Han, Li Li, Siyu Zhou, Yuqiang Gong, Binyu Ying, Fang Gao-Smith, Shengwei Jin
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
acute respiratory distress syndrome
alveolar fluid clearance
ENaC
Na,K-ATPase
ubiquitination
erythropoietin
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224003317

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