Effect of the Proximal Anastomosis Configuration of the Radial Artery in Patients Undergoing Coronary Artery Bypass Grafting

Background: Several factors, such as the degree of target vessel stenosis, are known to be associated with radial artery (RA) graft patency in coronary artery bypass grafting (CABG). There is a lack of data regarding the effect of the RA proximal configuration (aortic anastomosis versus T-anastom...

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Main Authors: Seung Keun Yoon, Hyun Song, Ju Yong Lim
Format: Article
Language:English
Published: Korean Society for Thoracic & Cardiovascular Surgery 2021-04-01
Series:Journal of Chest Surgery
Subjects:
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author Seung Keun Yoon
Hyun Song
Ju Yong Lim
author_facet Seung Keun Yoon
Hyun Song
Ju Yong Lim
author_sort Seung Keun Yoon
collection DOAJ
description Background: Several factors, such as the degree of target vessel stenosis, are known to be associated with radial artery (RA) graft patency in coronary artery bypass grafting (CABG). There is a lack of data regarding the effect of the RA proximal configuration (aortic anastomosis versus T-anastomosis). This study evaluated the effects of the RA proximal configuration on the patency rate and clinical outcomes after CABG. Methods: We conducted a retrospective study, analyzing 328 patients who had undergone CABG with an RA graft. We divided the patients into 2 groups. The primary endpoint was RA patency and the secondary endpoints were overall mortality and major adverse cardiac and cerebrovascular events (MACCE). We performed a propensity score-matched comparison. Results: Aorta-RA anastomosis was performed in 275 patients, whereas the rest of the 53 patients received T-RA anastomosis. The mean age was 67.3±8.7 years in the T-RA anastomosis group and 63.8±9.5 years in the aorta-RA anastomosis group (p=0.02). The mean follow-up duration was 5.13±3.07 years. Target vessel stenosis ≥70% (hazard ratio [HR], 0.42; 95% confidence interval [CI], 0.20–0.91; p=0.03) and T-RA anastomosis configuration (HR, 2.34; 95% CI, 1.01–5.19; p=0.04) were significantly associated with RA occlusion in the multivariable analysis. However, T-RA anastomosis was not associated with higher risks of overall mortality and MACCE following CABG (p=0.30 and p=0.07 in the matched group, respectively). Conclusion: Aorta-RA anastomosis showed a superior patency rate compared to T-RA anastomosis. However, the RA proximal anastomosis configuration was not associated with mortality or MACCE.
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spelling doaj.art-7740ac1317384169942acc3b6f374bba2022-12-21T19:53:11ZengKorean Society for Thoracic & Cardiovascular SurgeryJournal of Chest Surgery2765-16062765-16142021-04-0154211712610.5090/jcs.20.082Effect of the Proximal Anastomosis Configuration of the Radial Artery in Patients Undergoing Coronary Artery Bypass GraftingSeung Keun Yoon0Hyun Song1Ju Yong Lim2The Catholic University of KoreaThe Catholic University of KoreaThe Catholic University of KoreaBackground: Several factors, such as the degree of target vessel stenosis, are known to be associated with radial artery (RA) graft patency in coronary artery bypass grafting (CABG). There is a lack of data regarding the effect of the RA proximal configuration (aortic anastomosis versus T-anastomosis). This study evaluated the effects of the RA proximal configuration on the patency rate and clinical outcomes after CABG. Methods: We conducted a retrospective study, analyzing 328 patients who had undergone CABG with an RA graft. We divided the patients into 2 groups. The primary endpoint was RA patency and the secondary endpoints were overall mortality and major adverse cardiac and cerebrovascular events (MACCE). We performed a propensity score-matched comparison. Results: Aorta-RA anastomosis was performed in 275 patients, whereas the rest of the 53 patients received T-RA anastomosis. The mean age was 67.3±8.7 years in the T-RA anastomosis group and 63.8±9.5 years in the aorta-RA anastomosis group (p=0.02). The mean follow-up duration was 5.13±3.07 years. Target vessel stenosis ≥70% (hazard ratio [HR], 0.42; 95% confidence interval [CI], 0.20–0.91; p=0.03) and T-RA anastomosis configuration (HR, 2.34; 95% CI, 1.01–5.19; p=0.04) were significantly associated with RA occlusion in the multivariable analysis. However, T-RA anastomosis was not associated with higher risks of overall mortality and MACCE following CABG (p=0.30 and p=0.07 in the matched group, respectively). Conclusion: Aorta-RA anastomosis showed a superior patency rate compared to T-RA anastomosis. However, the RA proximal anastomosis configuration was not associated with mortality or MACCE.coronary artery bypass graftingradial arteryvascular patencyvascular graft occlusionsurgical anastomosis
spellingShingle Seung Keun Yoon
Hyun Song
Ju Yong Lim
Effect of the Proximal Anastomosis Configuration of the Radial Artery in Patients Undergoing Coronary Artery Bypass Grafting
Journal of Chest Surgery
coronary artery bypass grafting
radial artery
vascular patency
vascular graft occlusion
surgical anastomosis
title Effect of the Proximal Anastomosis Configuration of the Radial Artery in Patients Undergoing Coronary Artery Bypass Grafting
title_full Effect of the Proximal Anastomosis Configuration of the Radial Artery in Patients Undergoing Coronary Artery Bypass Grafting
title_fullStr Effect of the Proximal Anastomosis Configuration of the Radial Artery in Patients Undergoing Coronary Artery Bypass Grafting
title_full_unstemmed Effect of the Proximal Anastomosis Configuration of the Radial Artery in Patients Undergoing Coronary Artery Bypass Grafting
title_short Effect of the Proximal Anastomosis Configuration of the Radial Artery in Patients Undergoing Coronary Artery Bypass Grafting
title_sort effect of the proximal anastomosis configuration of the radial artery in patients undergoing coronary artery bypass grafting
topic coronary artery bypass grafting
radial artery
vascular patency
vascular graft occlusion
surgical anastomosis
work_keys_str_mv AT seungkeunyoon effectoftheproximalanastomosisconfigurationoftheradialarteryinpatientsundergoingcoronaryarterybypassgrafting
AT hyunsong effectoftheproximalanastomosisconfigurationoftheradialarteryinpatientsundergoingcoronaryarterybypassgrafting
AT juyonglim effectoftheproximalanastomosisconfigurationoftheradialarteryinpatientsundergoingcoronaryarterybypassgrafting