A simple flash and freeze system for cryogenic time-resolved electron microscopy

A simple flash and freeze system for cryogenic time-resolved electron microscopy

As the resolution revolution in CryoEM expands to encompass all manner of macromolecular complexes, an important new frontier is the implementation of cryogenic time resolved EM (cryoTREM). Biological macromolecular complexes are dynamic systems that undergo conformational changes on timescales from...

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Bibliographic Details
Main Authors: Biddut Bhattacharjee, Md Mahfuzur Rahman, Ryan E. Hibbs, Michael H. B. Stowell
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
CryoEM
time resolved
LED
optogenetic activation
caged compounds
plunge freezer
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1129225/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1129225/full

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