Upregulation of Runt related transcription factor 1 (RUNX1) contributes to tendon–bone healing after anterior cruciate ligament reconstruction using bone mesenchymal stem cells

Abstract Background Anterior cruciate ligament (ACL) injury could lead to functional impairment along with disabilities. ACL reconstruction often fails owing to the regeneration failure of tendon–bone interface. Herein, we aimed to investigate the effects of Runt related transcription factor 1 (RUNX...

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Bibliographic Details
Main Authors: Kai Kang, Qian Geng, Lukuan Cui, Lijie Wu, Lei Zhang, Tong Li, Qian Zhang, Shijun Gao
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-022-03152-y