MALDI-TOF INVESTIGATION OF LYSOZYME-ALBUMIN INTERACTION
Proteins are the main components of living systems therefore they are a subject of study from different points of view. Under certain conditions, proteins are capable of self-organization forming oligomeric structures of various composition and new properties. The investigations of these transformat...
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| Format: | Article |
| Language: | English |
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Academy of Sciences of Moldova, Institute of Chemistry
2014-12-01
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| Series: | Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry |
| Subjects: | |
| Online Access: | http://www.cjm.asm.md/sites/default/files/article_files/Chemistry%20nr%202%202014%20p%20107-110.pdf |
| _version_ | 1831551905518583808 |
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| author | Marharyta Vasylieva Taras Gromovoy |
| author_facet | Marharyta Vasylieva Taras Gromovoy |
| author_sort | Marharyta Vasylieva |
| collection | DOAJ |
| description | Proteins are the main components of living systems therefore they are a subject of study from different points of view. Under certain conditions, proteins are capable of self-organization forming oligomeric structures of various composition and new properties. The investigations of these transformations were carried out on two well known proteins: albumin and lyzozyme. It is shown that with increase in the concentration of lysozyme in relation to that of albumin the intensities of the peaks corresponding to associates, related to the intensities of the peaks corresponding to albumin and lysozyme, are also increased. Associates of albumin and lysozyme are forming in the stoichiometric ratios of 1:1, 1:2, 1:3, 1:4. A similar pattern is observed in the case of albumin dimer. |
| first_indexed | 2024-12-17T03:17:14Z |
| format | Article |
| id | doaj.art-7742dc5c16e54b338c7522dfbed9905b |
| institution | Directory Open Access Journal |
| issn | 1857-1727 2345-1688 |
| language | English |
| last_indexed | 2024-12-17T03:17:14Z |
| publishDate | 2014-12-01 |
| publisher | Academy of Sciences of Moldova, Institute of Chemistry |
| record_format | Article |
| series | Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry |
| spelling | doaj.art-7742dc5c16e54b338c7522dfbed9905b2022-12-21T22:05:37ZengAcademy of Sciences of Moldova, Institute of ChemistryChemistry Journal of Moldova: General, Industrial and Ecological Chemistry1857-17272345-16882014-12-0192107110MALDI-TOF INVESTIGATION OF LYSOZYME-ALBUMIN INTERACTIONMarharyta Vasylieva0Taras Gromovoy1О. Chuiko Institute of Surface Chemistry, National Academy of Sciences of UkraineО. Chuiko Institute of Surface Chemistry, National Academy of Sciences of UkraineProteins are the main components of living systems therefore they are a subject of study from different points of view. Under certain conditions, proteins are capable of self-organization forming oligomeric structures of various composition and new properties. The investigations of these transformations were carried out on two well known proteins: albumin and lyzozyme. It is shown that with increase in the concentration of lysozyme in relation to that of albumin the intensities of the peaks corresponding to associates, related to the intensities of the peaks corresponding to albumin and lysozyme, are also increased. Associates of albumin and lysozyme are forming in the stoichiometric ratios of 1:1, 1:2, 1:3, 1:4. A similar pattern is observed in the case of albumin dimer.http://www.cjm.asm.md/sites/default/files/article_files/Chemistry%20nr%202%202014%20p%20107-110.pdfMALDI-TOFalbuminlysozymeprotein-protein interaction |
| spellingShingle | Marharyta Vasylieva Taras Gromovoy MALDI-TOF INVESTIGATION OF LYSOZYME-ALBUMIN INTERACTION Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry MALDI-TOF albumin lysozyme protein-protein interaction |
| title | MALDI-TOF INVESTIGATION OF LYSOZYME-ALBUMIN INTERACTION |
| title_full | MALDI-TOF INVESTIGATION OF LYSOZYME-ALBUMIN INTERACTION |
| title_fullStr | MALDI-TOF INVESTIGATION OF LYSOZYME-ALBUMIN INTERACTION |
| title_full_unstemmed | MALDI-TOF INVESTIGATION OF LYSOZYME-ALBUMIN INTERACTION |
| title_short | MALDI-TOF INVESTIGATION OF LYSOZYME-ALBUMIN INTERACTION |
| title_sort | maldi tof investigation of lysozyme albumin interaction |
| topic | MALDI-TOF albumin lysozyme protein-protein interaction |
| url | http://www.cjm.asm.md/sites/default/files/article_files/Chemistry%20nr%202%202014%20p%20107-110.pdf |
| work_keys_str_mv | AT marharytavasylieva malditofinvestigationoflysozymealbumininteraction AT tarasgromovoy malditofinvestigationoflysozymealbumininteraction |