Long-Term Prognosis of Patients with Myocardial Infarction Type 1 and Type 2 with and without Involvement of Coronary Vasospasm
While prognoses in relation to myocardial infarction (MI) type have been elucidated in past reports, the results were not consistent, perhaps due to occurrence of Type 2 MI with CVS and its mortality. The Japanese registry of acute Myocardial Infarction diagnosed by Universal Definition (J-MINUET) i...
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2020-06-01
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author | Ryota Sato Kenji Sakamoto Koichi Kaikita Kenichi Tsujita Koichi Nakao Yukio Ozaki Kazuo Kimura Junya Ako Teruo Noguchi Satoshi Yasuda Satoru Suwa Kazuteru Fujimoto Yasuharu Nakama Takashi Morita Wataru Shimizu Yoshihiko Saito Atsushi Hirohata Yasuhiro Morita Teruo Inoue Atsunori Okamura Toshiaki Mano Kazuhito Hirata Kengo Tanabe Yoshisato Shibata Mafumi Owa Hiroshi Funayama Nobuaki Kokubu Ken Kozuma Shirou Uemura Tetsuya Toubaru Keijirou Saku Shigeru Ohshima Kunihiro Nishimura Yoshihiro Miyamoto Hisao Ogawa Masaharu Ishihara |
author_facet | Ryota Sato Kenji Sakamoto Koichi Kaikita Kenichi Tsujita Koichi Nakao Yukio Ozaki Kazuo Kimura Junya Ako Teruo Noguchi Satoshi Yasuda Satoru Suwa Kazuteru Fujimoto Yasuharu Nakama Takashi Morita Wataru Shimizu Yoshihiko Saito Atsushi Hirohata Yasuhiro Morita Teruo Inoue Atsunori Okamura Toshiaki Mano Kazuhito Hirata Kengo Tanabe Yoshisato Shibata Mafumi Owa Hiroshi Funayama Nobuaki Kokubu Ken Kozuma Shirou Uemura Tetsuya Toubaru Keijirou Saku Shigeru Ohshima Kunihiro Nishimura Yoshihiro Miyamoto Hisao Ogawa Masaharu Ishihara |
author_sort | Ryota Sato |
collection | DOAJ |
description | While prognoses in relation to myocardial infarction (MI) type have been elucidated in past reports, the results were not consistent, perhaps due to occurrence of Type 2 MI with CVS and its mortality. The Japanese registry of acute Myocardial Infarction diagnosed by Universal Definition (J-MINUET) is a prospective multicenter registry in Japan. In contrast to thromboembolic event-related Type 1 myocardial infarction (MI), clinical features of Type 2 MI, including coronary vasospasm (CVS), are varied due to the heterogeneous nature of its development. To elucidate the MI type-related all-cause mortality, 2989 consecutive patients with AMI were stratified as Type 1 MI, Type 2 MI with CVS, and Type 2 MI with non-CVS. Most patients (<i>n</i> = 2834; 94.8%) were classified as Type 1 MI and 155 patients (5.2%) were classified as Type 2 MI. Of the Type 2 MI patients, 87 (56% of Type 2 MI) were diagnosed as MI with CVS. Although the 3-year mortality was comparable between Type 1 and Type 2 MI patients, significant differences were observed between Type 2 MI with CVS and with non-CVS (3.4% and 22.1%, <i>p</i> < 0.001). Among Japanese patients with AMI, mortality rates between Type 1 MI and Type 2 MI are comparable, but further stratification of Type 2 MI (with or without CVS) may be useful in predicting the prognosis of patients with Type 2 MI. |
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spelling | doaj.art-7743977d9b5d4270b5258bc6ebb79bbb2023-11-20T02:33:58ZengMDPI AGJournal of Clinical Medicine2077-03832020-06-0196168610.3390/jcm9061686Long-Term Prognosis of Patients with Myocardial Infarction Type 1 and Type 2 with and without Involvement of Coronary VasospasmRyota Sato0Kenji Sakamoto1Koichi Kaikita2Kenichi Tsujita3Koichi Nakao4Yukio Ozaki5Kazuo Kimura6Junya Ako7Teruo Noguchi8Satoshi Yasuda9Satoru Suwa10Kazuteru Fujimoto11Yasuharu Nakama12Takashi Morita13Wataru Shimizu14Yoshihiko Saito15Atsushi Hirohata16Yasuhiro Morita17Teruo Inoue18Atsunori Okamura19Toshiaki Mano20Kazuhito Hirata21Kengo Tanabe22Yoshisato Shibata23Mafumi Owa24Hiroshi Funayama25Nobuaki Kokubu26Ken Kozuma27Shirou Uemura28Tetsuya Toubaru29Keijirou Saku30Shigeru Ohshima31Kunihiro Nishimura32Yoshihiro Miyamoto33Hisao Ogawa34Masaharu Ishihara35Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, JapanDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, JapanDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, JapanDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, JapanDivision of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center, Kumamoto 861-4193, JapanDepartment of Cardiology, Fujita Health University, Toyoake 470-1101, JapanCardiovascular Center, Yokohama City University Medical Center, Yokohama 236-0004, JapanDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara 252-0375, JapanDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita 565-8565, JapanDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita 565-8565, JapanDepartment of Cardiology, Juntendo University Shizuoka Hospital, Izunokuni 410-2295, JapanDepartment of Cardiology, National Hospital Organization Kumamoto Medical Center, Kumamoto 860-0008, JapanDepartment of Cardiology, Hiroshima City Hospital, Hiroshima 730-8518, JapanDivision of Cardiology, Osaka General Medical Center, Osaka 558-8558, JapanDepartment of Cardiovascular Medicine, Nippon Medical School, Tokyo 113-8603, JapanFirst Department of Internal Medicine, Nara Medical University, Kashihara 634-8521, JapanDepartment of Cardiovascular Medicine, The Sakakibara Heart Institute of Okayama, Okayama 700-0804, JapanDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki 503-8502, JapanDepartment of Cardiovascular Medicine, Dokkyo Medical University, Tochigi 321-0293, JapanDepartment of Cardiology, Sakurabashi Watanabe Hospital, Osaka 530-0001, JapanInstitute for Clinical Research, Kansai Rosai Hospital, Osaka 660-8511, JapanDepartment of Cardiology, Okinawa Chubu Hospital, Uruma 904-2293, JapanDivision of Cardiology, Mitsui Memorial Hospital, Tokyo 101-8043, JapanDepartment of Cardiology, Miyazaki Medical Association Hospital, Miyazaki 880-0834, JapanDepartment of Cardiovascular Medicine, Suwa Red Cross Hospital, Suwa 392-8510, JapanDivision of Cardiovascular Medicine, Saitama Medical Center Jichi Medical University, Saitama 330-8503, JapanDepartment of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University, Sapporo 060-8543, JapanDepartment of Cardiology, Teikyo University, Tokyo 173-8606, JapanDepartment of Cardiology, Kawasaki Medical School, Kurashiki 701-0192, JapanDepartment of Cardiology, Sakakibara Heart Institute, Tokyo 183-0003, JapanDepartment of Cardiology, Fukuoka University School of Medicine, Fukuoka 814-0133, JapanDepartment of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi 371-0004, JapanDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita 565-8565, JapanDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita 565-8565, JapanDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita 565-8565, JapanDepartment of Cardiovascular and Renal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, JapanWhile prognoses in relation to myocardial infarction (MI) type have been elucidated in past reports, the results were not consistent, perhaps due to occurrence of Type 2 MI with CVS and its mortality. The Japanese registry of acute Myocardial Infarction diagnosed by Universal Definition (J-MINUET) is a prospective multicenter registry in Japan. In contrast to thromboembolic event-related Type 1 myocardial infarction (MI), clinical features of Type 2 MI, including coronary vasospasm (CVS), are varied due to the heterogeneous nature of its development. To elucidate the MI type-related all-cause mortality, 2989 consecutive patients with AMI were stratified as Type 1 MI, Type 2 MI with CVS, and Type 2 MI with non-CVS. Most patients (<i>n</i> = 2834; 94.8%) were classified as Type 1 MI and 155 patients (5.2%) were classified as Type 2 MI. Of the Type 2 MI patients, 87 (56% of Type 2 MI) were diagnosed as MI with CVS. Although the 3-year mortality was comparable between Type 1 and Type 2 MI patients, significant differences were observed between Type 2 MI with CVS and with non-CVS (3.4% and 22.1%, <i>p</i> < 0.001). Among Japanese patients with AMI, mortality rates between Type 1 MI and Type 2 MI are comparable, but further stratification of Type 2 MI (with or without CVS) may be useful in predicting the prognosis of patients with Type 2 MI.https://www.mdpi.com/2077-0383/9/6/1686acute myocardial infarctionclinical outcomescoronary vasospasmuniversal definition of myocardial infarction |
spellingShingle | Ryota Sato Kenji Sakamoto Koichi Kaikita Kenichi Tsujita Koichi Nakao Yukio Ozaki Kazuo Kimura Junya Ako Teruo Noguchi Satoshi Yasuda Satoru Suwa Kazuteru Fujimoto Yasuharu Nakama Takashi Morita Wataru Shimizu Yoshihiko Saito Atsushi Hirohata Yasuhiro Morita Teruo Inoue Atsunori Okamura Toshiaki Mano Kazuhito Hirata Kengo Tanabe Yoshisato Shibata Mafumi Owa Hiroshi Funayama Nobuaki Kokubu Ken Kozuma Shirou Uemura Tetsuya Toubaru Keijirou Saku Shigeru Ohshima Kunihiro Nishimura Yoshihiro Miyamoto Hisao Ogawa Masaharu Ishihara Long-Term Prognosis of Patients with Myocardial Infarction Type 1 and Type 2 with and without Involvement of Coronary Vasospasm Journal of Clinical Medicine acute myocardial infarction clinical outcomes coronary vasospasm universal definition of myocardial infarction |
title | Long-Term Prognosis of Patients with Myocardial Infarction Type 1 and Type 2 with and without Involvement of Coronary Vasospasm |
title_full | Long-Term Prognosis of Patients with Myocardial Infarction Type 1 and Type 2 with and without Involvement of Coronary Vasospasm |
title_fullStr | Long-Term Prognosis of Patients with Myocardial Infarction Type 1 and Type 2 with and without Involvement of Coronary Vasospasm |
title_full_unstemmed | Long-Term Prognosis of Patients with Myocardial Infarction Type 1 and Type 2 with and without Involvement of Coronary Vasospasm |
title_short | Long-Term Prognosis of Patients with Myocardial Infarction Type 1 and Type 2 with and without Involvement of Coronary Vasospasm |
title_sort | long term prognosis of patients with myocardial infarction type 1 and type 2 with and without involvement of coronary vasospasm |
topic | acute myocardial infarction clinical outcomes coronary vasospasm universal definition of myocardial infarction |
url | https://www.mdpi.com/2077-0383/9/6/1686 |
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