The Key Role of IP<sub>6</sub>K: A Novel Target for Anticancer Treatments?

The Key Role of IP<sub>6</sub>K: A Novel Target for Anticancer Treatments?

Inositol and its phosphate metabolites play a pivotal role in several biochemical pathways and gene expression regulation: inositol pyrophosphates (PP-IPs) have been increasingly appreciated as key signaling modulators. Fluctuations in their intracellular levels hugely impact the transfer of phospha...

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Bibliographic Details
Main Authors: Mirko Minini, Alice Senni, Vittorio Unfer, Mariano Bizzarri
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
inositol pyrophosphates (PP-IPs)
diphosphoinositol pentakisphosphate (5-IP<sub>7</sub> or IP<sub>7</sub>)
inositol hexakisphosphate kinase (IP<sub>6</sub>K)
<i>myo</i>-inositol
anticancer activity
Online Access:https://www.mdpi.com/1420-3049/25/19/4401

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