Impaired Regulation by IL-35 in Systemic Sclerosis

Impaired Regulation by IL-35 in Systemic Sclerosis

This study investigated the role of IL-35 in systemic sclerosis (SSc) patients, focusing on CD4+ T cell response and immunomodulatory cytokine production. By comparing the cytokine levels in healthy donors (HD) and SSc patients using ELISAs, we found a significantly lower plasma IL-35 concentration...

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Bibliographic Details
Main Authors: Rubén Osuna-Gómez, Ivan Castellví, Maria Mulet, Mª Àngels Ortiz, Douglas E. Brough, Helen Sabzevari, Roshanak T. Semnani, Silvia Vidal
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
systemic sclerosis
interleukin-35
CD4+ T lymphocytes
regulatory T cells
Online Access:https://www.mdpi.com/1422-0067/24/13/10567

Internet

https://www.mdpi.com/1422-0067/24/13/10567

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