Highly Responsive Chitosan-Co-Poly (MAA) Nanomatrices through Cross-Linking Polymerization for Solubility Improvement

Highly Responsive Chitosan-Co-Poly (MAA) Nanomatrices through Cross-Linking Polymerization for Solubility Improvement

In this study, we report the highly responsive chitosan-based chemically cross-linked nanomatrices, a nano-version of hydrogels developed through modified polymerization reaction for solubility improvement of poorly soluble drug simvastatin. The developed nanomatrices were characterized for solubili...

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Bibliographic Details
Main Authors: Anam Saleem, Naveed Akhtar, Muhammad Usman Minhas, Arshad Mahmood, Kifayat Ullah Khan, Orva Abdullah
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Gels
Subjects:
nanomatrices
solubility enhancement
simvastatin
chitosan
toxicological evaluation
Online Access:https://www.mdpi.com/2310-2861/8/3/196

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