Evaluation of oncofertility care in childhood cancer patients: the EU-Horizon 2020 twinning project TREL initiative
BackgroundThe 5-year survival rate of childhood cancer exceeds 80%, however, many survivors develop late effects including infertility. The aim of this study was to evaluate the current status of oncofertility care at Vilnius University Hospital Santaros Klinikos (VULSK) within the framework of the...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-07-01
|
| Series: | Frontiers in Pediatrics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2023.1212711/full |
| _version_ | 1797772182186622976 |
|---|---|
| author | Egle Stukaite-Ruibiene M. E. Madeleine van der Perk Goda Elizabeta Vaitkeviciene Goda Elizabeta Vaitkeviciene Annelies M. E. Bos Zana Bumbuliene Zana Bumbuliene Marry M. van den Heuvel-Eibrink Jelena Rascon Jelena Rascon |
| author_facet | Egle Stukaite-Ruibiene M. E. Madeleine van der Perk Goda Elizabeta Vaitkeviciene Goda Elizabeta Vaitkeviciene Annelies M. E. Bos Zana Bumbuliene Zana Bumbuliene Marry M. van den Heuvel-Eibrink Jelena Rascon Jelena Rascon |
| author_sort | Egle Stukaite-Ruibiene |
| collection | DOAJ |
| description | BackgroundThe 5-year survival rate of childhood cancer exceeds 80%, however, many survivors develop late effects including infertility. The aim of this study was to evaluate the current status of oncofertility care at Vilnius University Hospital Santaros Klinikos (VULSK) within the framework of the EU-Horizon 2020 TREL project.MethodsAll parents or patients aged 12–17.9 years treated from July 1, 2021 until July 1, 2022 were invited to complete an oncofertility-care-evaluation questionnaire. After completing the questionnaire, patients were triaged to low-risk (LR) or high-risk (HR) of gonadal damage using a risk stratification tool (triage). Data was assessed using descriptive statistics.ResultsQuestionnaires were completed by 48 parents and 13 children triaged as 36 (59%) LR and 25 (41%) HR patients. Most HR respondents (21/25, 84%) were not counseled by a fertility specialist. Six boys (4 HR, 2 LR) were counseled, none of the girls was counseled. Three HR boys underwent sperm cryopreservation. Only 17 (27.9%, 9 HR, 8 LR) respondents correctly estimated their risk. All counseled boys (n = 6) agreed the risk for fertility impairment had been mentioned as compared to 49.1% (n = 27) of uncounseled. All counseled respondents agreed they knew enough about fertility (vs. 42%).ConclusionsRespondents counseled by a fertility specialist were provided more information on fertility than uncounseled. HR patients were not sufficiently counseled by a fertility specialist. Based on the current experience oncofertility care at VULSK will be improved. |
| first_indexed | 2024-03-12T21:47:18Z |
| format | Article |
| id | doaj.art-775b9473c2a8480a864922538bedaddb |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-03-12T21:47:18Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-775b9473c2a8480a864922538bedaddb2023-07-26T08:07:46ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602023-07-011110.3389/fped.2023.12127111212711Evaluation of oncofertility care in childhood cancer patients: the EU-Horizon 2020 twinning project TREL initiativeEgle Stukaite-Ruibiene0M. E. Madeleine van der Perk1Goda Elizabeta Vaitkeviciene2Goda Elizabeta Vaitkeviciene3Annelies M. E. Bos4Zana Bumbuliene5Zana Bumbuliene6Marry M. van den Heuvel-Eibrink7Jelena Rascon8Jelena Rascon9Faculty of Medicine, Vilnius University, Vilnius, LithuaniaPrincess Máxima Center for Pediatric Oncology, Utrecht, NetherlandsFaculty of Medicine, Vilnius University, Vilnius, LithuaniaCenter for Pediatric Oncology and Hematology, Vilnius University Hospital Santaros Klinikos, Vilnius, LithuaniaPrincess Máxima Center for Pediatric Oncology, Utrecht, NetherlandsFaculty of Medicine, Vilnius University, Vilnius, LithuaniaCenter of Obstetrics and Gynecology, Vilnius University Hospital Santaros Klinikos, Vilnius, LithuaniaPrincess Máxima Center for Pediatric Oncology, Utrecht, NetherlandsFaculty of Medicine, Vilnius University, Vilnius, LithuaniaCenter for Pediatric Oncology and Hematology, Vilnius University Hospital Santaros Klinikos, Vilnius, LithuaniaBackgroundThe 5-year survival rate of childhood cancer exceeds 80%, however, many survivors develop late effects including infertility. The aim of this study was to evaluate the current status of oncofertility care at Vilnius University Hospital Santaros Klinikos (VULSK) within the framework of the EU-Horizon 2020 TREL project.MethodsAll parents or patients aged 12–17.9 years treated from July 1, 2021 until July 1, 2022 were invited to complete an oncofertility-care-evaluation questionnaire. After completing the questionnaire, patients were triaged to low-risk (LR) or high-risk (HR) of gonadal damage using a risk stratification tool (triage). Data was assessed using descriptive statistics.ResultsQuestionnaires were completed by 48 parents and 13 children triaged as 36 (59%) LR and 25 (41%) HR patients. Most HR respondents (21/25, 84%) were not counseled by a fertility specialist. Six boys (4 HR, 2 LR) were counseled, none of the girls was counseled. Three HR boys underwent sperm cryopreservation. Only 17 (27.9%, 9 HR, 8 LR) respondents correctly estimated their risk. All counseled boys (n = 6) agreed the risk for fertility impairment had been mentioned as compared to 49.1% (n = 27) of uncounseled. All counseled respondents agreed they knew enough about fertility (vs. 42%).ConclusionsRespondents counseled by a fertility specialist were provided more information on fertility than uncounseled. HR patients were not sufficiently counseled by a fertility specialist. Based on the current experience oncofertility care at VULSK will be improved.https://www.frontiersin.org/articles/10.3389/fped.2023.1212711/fullchildhood cancerfertility counselinglate effectsquestionnairetwinning |
| spellingShingle | Egle Stukaite-Ruibiene M. E. Madeleine van der Perk Goda Elizabeta Vaitkeviciene Goda Elizabeta Vaitkeviciene Annelies M. E. Bos Zana Bumbuliene Zana Bumbuliene Marry M. van den Heuvel-Eibrink Jelena Rascon Jelena Rascon Evaluation of oncofertility care in childhood cancer patients: the EU-Horizon 2020 twinning project TREL initiative Frontiers in Pediatrics childhood cancer fertility counseling late effects questionnaire twinning |
| title | Evaluation of oncofertility care in childhood cancer patients: the EU-Horizon 2020 twinning project TREL initiative |
| title_full | Evaluation of oncofertility care in childhood cancer patients: the EU-Horizon 2020 twinning project TREL initiative |
| title_fullStr | Evaluation of oncofertility care in childhood cancer patients: the EU-Horizon 2020 twinning project TREL initiative |
| title_full_unstemmed | Evaluation of oncofertility care in childhood cancer patients: the EU-Horizon 2020 twinning project TREL initiative |
| title_short | Evaluation of oncofertility care in childhood cancer patients: the EU-Horizon 2020 twinning project TREL initiative |
| title_sort | evaluation of oncofertility care in childhood cancer patients the eu horizon 2020 twinning project trel initiative |
| topic | childhood cancer fertility counseling late effects questionnaire twinning |
| url | https://www.frontiersin.org/articles/10.3389/fped.2023.1212711/full |
| work_keys_str_mv | AT eglestukaiteruibiene evaluationofoncofertilitycareinchildhoodcancerpatientstheeuhorizon2020twinningprojecttrelinitiative AT memadeleinevanderperk evaluationofoncofertilitycareinchildhoodcancerpatientstheeuhorizon2020twinningprojecttrelinitiative AT godaelizabetavaitkeviciene evaluationofoncofertilitycareinchildhoodcancerpatientstheeuhorizon2020twinningprojecttrelinitiative AT godaelizabetavaitkeviciene evaluationofoncofertilitycareinchildhoodcancerpatientstheeuhorizon2020twinningprojecttrelinitiative AT anneliesmebos evaluationofoncofertilitycareinchildhoodcancerpatientstheeuhorizon2020twinningprojecttrelinitiative AT zanabumbuliene evaluationofoncofertilitycareinchildhoodcancerpatientstheeuhorizon2020twinningprojecttrelinitiative AT zanabumbuliene evaluationofoncofertilitycareinchildhoodcancerpatientstheeuhorizon2020twinningprojecttrelinitiative AT marrymvandenheuveleibrink evaluationofoncofertilitycareinchildhoodcancerpatientstheeuhorizon2020twinningprojecttrelinitiative AT jelenarascon evaluationofoncofertilitycareinchildhoodcancerpatientstheeuhorizon2020twinningprojecttrelinitiative AT jelenarascon evaluationofoncofertilitycareinchildhoodcancerpatientstheeuhorizon2020twinningprojecttrelinitiative |