Management of Childhood Glaucoma Following Cataract Surgery

Glaucoma remains a frequent serious complication following cataract surgery in children. The optimal approach to management for ‘glaucoma following cataract surgery’ (GFCS), one of the paediatric glaucoma subtypes, is an ongoing debate. This review evaluates the various management options available...

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Main Authors: Anne-Sophie Simons, Ingele Casteels, John Grigg, Ingeborg Stalmans, Evelien Vandewalle, Sophie Lemmens
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/4/1041
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author Anne-Sophie Simons
Ingele Casteels
John Grigg
Ingeborg Stalmans
Evelien Vandewalle
Sophie Lemmens
author_facet Anne-Sophie Simons
Ingele Casteels
John Grigg
Ingeborg Stalmans
Evelien Vandewalle
Sophie Lemmens
author_sort Anne-Sophie Simons
collection DOAJ
description Glaucoma remains a frequent serious complication following cataract surgery in children. The optimal approach to management for ‘glaucoma following cataract surgery’ (GFCS), one of the paediatric glaucoma subtypes, is an ongoing debate. This review evaluates the various management options available and aims to propose a clinical management strategy for GFCS cases. A literature search was conducted in four large databases (Cochrane, PubMed, Embase, and Web of Science), from 1995 up to December 2021. Thirty-nine studies—presenting (1) eyes with GFCS; a disease entity as defined by the Childhood Glaucoma Research Network Classification, (2) data on treatment outcomes, and (3) follow-up data of at least 6 months—were included. Included papers report on GFCS treated with angle surgery, trabeculectomy, glaucoma drainage device implantation (GDD), and cyclodestructive procedures. Medical therapy is the first-line treatment in GFCS, possibly to bridge time to surgery. Multiple surgical procedures are often required to adequately control GFCS. Angle surgery (360 degree) may be considered before proceeding to GDD implantation, since this technique offers good results and is less invasive. Literature suggests that GDD implantation gives the best chance for long-term IOP control in childhood GFCS and some studies put this technique forward as a good choice for primary surgery. Cyclodestruction seems to be effective in some cases with uncontrolled IOP. Trabeculectomy should be avoided, especially in children under the age of one year and children that are left aphakic. The authors provide a flowchart to guide the management of individual GFCS cases.
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spelling doaj.art-775c06efacda45aea29405cda4c58d512023-11-23T20:30:52ZengMDPI AGJournal of Clinical Medicine2077-03832022-02-01114104110.3390/jcm11041041Management of Childhood Glaucoma Following Cataract SurgeryAnne-Sophie Simons0Ingele Casteels1John Grigg2Ingeborg Stalmans3Evelien Vandewalle4Sophie Lemmens5Department of Ophthalmology, University Hospitals UZ Leuven, Herestraat 49, 3000 Leuven, BelgiumDepartment of Ophthalmology, University Hospitals UZ Leuven, Herestraat 49, 3000 Leuven, BelgiumFaculty of Medicine and Health, Save Sight Institute, The University of Sydney, 8 Macquarie St., Sydney, NSW 2000, AustraliaDepartment of Ophthalmology, University Hospitals UZ Leuven, Herestraat 49, 3000 Leuven, BelgiumDepartment of Ophthalmology, University Hospitals UZ Leuven, Herestraat 49, 3000 Leuven, BelgiumDepartment of Ophthalmology, University Hospitals UZ Leuven, Herestraat 49, 3000 Leuven, BelgiumGlaucoma remains a frequent serious complication following cataract surgery in children. The optimal approach to management for ‘glaucoma following cataract surgery’ (GFCS), one of the paediatric glaucoma subtypes, is an ongoing debate. This review evaluates the various management options available and aims to propose a clinical management strategy for GFCS cases. A literature search was conducted in four large databases (Cochrane, PubMed, Embase, and Web of Science), from 1995 up to December 2021. Thirty-nine studies—presenting (1) eyes with GFCS; a disease entity as defined by the Childhood Glaucoma Research Network Classification, (2) data on treatment outcomes, and (3) follow-up data of at least 6 months—were included. Included papers report on GFCS treated with angle surgery, trabeculectomy, glaucoma drainage device implantation (GDD), and cyclodestructive procedures. Medical therapy is the first-line treatment in GFCS, possibly to bridge time to surgery. Multiple surgical procedures are often required to adequately control GFCS. Angle surgery (360 degree) may be considered before proceeding to GDD implantation, since this technique offers good results and is less invasive. Literature suggests that GDD implantation gives the best chance for long-term IOP control in childhood GFCS and some studies put this technique forward as a good choice for primary surgery. Cyclodestruction seems to be effective in some cases with uncontrolled IOP. Trabeculectomy should be avoided, especially in children under the age of one year and children that are left aphakic. The authors provide a flowchart to guide the management of individual GFCS cases.https://www.mdpi.com/2077-0383/11/4/1041childhood glaucomaaphakiapseudophakiacataract surgerylensectomymanagement (or therapy)
spellingShingle Anne-Sophie Simons
Ingele Casteels
John Grigg
Ingeborg Stalmans
Evelien Vandewalle
Sophie Lemmens
Management of Childhood Glaucoma Following Cataract Surgery
Journal of Clinical Medicine
childhood glaucoma
aphakia
pseudophakia
cataract surgery
lensectomy
management (or therapy)
title Management of Childhood Glaucoma Following Cataract Surgery
title_full Management of Childhood Glaucoma Following Cataract Surgery
title_fullStr Management of Childhood Glaucoma Following Cataract Surgery
title_full_unstemmed Management of Childhood Glaucoma Following Cataract Surgery
title_short Management of Childhood Glaucoma Following Cataract Surgery
title_sort management of childhood glaucoma following cataract surgery
topic childhood glaucoma
aphakia
pseudophakia
cataract surgery
lensectomy
management (or therapy)
url https://www.mdpi.com/2077-0383/11/4/1041
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AT ingeborgstalmans managementofchildhoodglaucomafollowingcataractsurgery
AT evelienvandewalle managementofchildhoodglaucomafollowingcataractsurgery
AT sophielemmens managementofchildhoodglaucomafollowingcataractsurgery