RUNX2 Reverses p53-Induced Chemotherapy Resistance in Gastric Cancer

RUNX2 Reverses p53-Induced Chemotherapy Resistance in Gastric Cancer

Yuan Huang,1 Lu Liang,2 Yong-Xiang Zhao,3 Bi-Hui Yao,2 Rui-Min Zhang,3 Lei Song,2 Zhong-Tao Zhang1 1Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People’s Republic of China; 2Department of General Surgery, Baotou Central Hospital, Baotou, 01...

Full description

Bibliographic Details
Main Authors:	Huang Y, Liang L, Zhao YX, Yao BH, Zhang RM, Song L, Zhang ZT
Format:	Article
Language:	English
Published:	Dove Medical Press 2023-03-01
Series:	Pharmacogenomics and Personalized Medicine
Subjects:	gastric cancer runx2 platinum chemotherapy resistance
Online Access:	https://www.dovepress.com/runx2-reverses-p53-induced-chemotherapy-resistance-in-gastric-cancer-peer-reviewed-fulltext-article-PGPM

Similar Items

Identification of the hub genes RUNX2 and FN1 in gastric cancer
by: Han Chao, et al.
Published: (2020-05-01)

DKK1 as a robust predictor for adjuvant platinum chemotherapy benefit in resectable pStage II-III gastric cancer
by: Zhiyuan Fan, et al.
Published: (2023-01-01)

Serum miR-4530 sensitizes breast cancer to neoadjuvant chemotherapy by suppressing RUNX2
by: Wang XX, et al.
Published: (2018-10-01)

RUNX2 promotes gastric cancer progression through the transcriptional activation of MGAT5 and MMP13
by: Ying Wang, et al.
Published: (2023-05-01)

The Multiple Interactions of RUNX with the Hippo–YAP Pathway
by: Linda Shyue Huey Chuang, et al.
Published: (2021-10-01)

The Relationship between RUNX3 Expression, Nursing Strategies and Nutritional Status in Elderly Patients with Advanced Gastric Cancer
by: Wen SONG, et al.
Published: (2017-05-01)

RUNX Family in Hypoxic Microenvironment and Angiogenesis in Cancers
by: You Mie Lee
Published: (2022-10-01)

Blood Free-Circulating DNA Testing of Methylated RUNX3 Is Useful for Diagnosing Early Gastric Cancer
by: Eizaburou Hideura, et al.
Published: (2020-03-01)

The RUNX Family of Proteins, DNA Repair, and Cancer
by: Vaidehi Krishnan
Published: (2023-04-01)

<i>p53</i> Deficiency-Dependent Oncogenicity of Runx3
by: Kosei Ito, et al.
Published: (2023-04-01)

<i>RUNX3</i> Transcript Variants Have Distinct Roles in Ovarian Carcinoma and Differently Influence Platinum Sensitivity and Angiogenesis
by: Karolin Heinze, et al.
Published: (2021-01-01)

PLA2G4A and ACHE modulate lipid profiles via glycerophospholipid metabolism in platinum-resistant gastric cancer
by: Menglin Chen, et al.
Published: (2024-03-01)

Different Requirements of CBFB and RUNX2 in Skeletal Development among Calvaria, Limbs, Vertebrae and Ribs
by: Qing Jiang, et al.
Published: (2022-10-01)

Runx Transcription Factors in T Cells—What Is Beyond Thymic Development?
by: Svetlana Korinfskaya, et al.
Published: (2021-08-01)

Deregulated Gene Expression Profiles and Regulatory Networks in Adult and Pediatric RUNX1/RUNX1T1-Positive AML Patients
by: Peggy Kanellou, et al.
Published: (2023-03-01)

The RUNX/CBFβ Complex in Breast Cancer: A Conundrum of Context
by: Adiba S. Khan, et al.
Published: (2023-02-01)

RUNX2 mutations in Taiwanese patients with cleidocranial dysplasia
by: Wei-De Lin, et al.
Published: (2011-01-01)

Impact of RUNX2 on drug-resistant human pancreatic cancer cells with p53 mutations
by: Toshinori Ozaki, et al.
Published: (2018-03-01)

Evaluation of CDH1;RUNX3 Expression in Cancerous and Normal Tissue of Patients With Gastric Cancer
by: M Einolghozati, et al.
Published: (2017-06-01)

Two Novel C-Terminus RUNX2 Mutations in Two Cleidocranial Dysplasia (CCD) Patients Impairing p53 Expression
by: Luca Dalle Carbonare, et al.
Published: (2021-09-01)

The RUNX Family Defines Trk Phenotype and Aggressiveness of Human Neuroblastoma through Regulation of p53 and MYCN
by: Kiyohiro Ando, et al.
Published: (2023-02-01)

Hemophagocytic Lymphohistiocytosis in RUNX1: : RUNX1T1 Positive AML with Blast Count Below 20%
by: Xingqin Huang, et al.
Published: (2023-08-01)

Aurora kinase-induced phosphorylation excludes transcription factor RUNX from the chromatin to facilitate proper mitotic progression
by: Chuang, Linda Shyue Huey, et al.
Published: (2017)

RUNX1 Is Regulated by Androgen Receptor to Promote Cancer Stem Markers and Chemotherapy Resistance in Triple Negative Breast Cancer
by: Natalia B. Fernández, et al.
Published: (2023-01-01)

Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling
by: Xiong Guo, et al.
Published: (2020-09-01)

The Roles of RUNX Proteins in Lymphocyte Function and Anti-Tumor Immunity
by: Wooseok Seo, et al.
Published: (2022-10-01)

RUNX Proteins as Epigenetic Modulators in Cancer
by: Hongyang Yi, et al.
Published: (2022-11-01)

RUNX2 and Cancer
by: Tsung-Chieh Lin
Published: (2023-04-01)

miR-30a-5p inhibits osteogenesis and promotes periodontitis by targeting Runx2
by: Xiangdong Liu, et al.
Published: (2021-10-01)

RUNX2 as a promising therapeutic target for malignant tumors
by: Zhao W, et al.
Published: (2021-03-01)

RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML
by: Justin Loke, et al.
Published: (2017-05-01)

RUNX3: A Location-oriented Genome Coordinator
by: Tianshu Xu, et al.
Published: (2023-05-01)

TLE4 Is a Critical Mediator of Osteoblast and Runx2-Dependent Bone Development
by: Thomas H. Shin, et al.
Published: (2021-08-01)

Prognostic significance of adjuvant chemotherapy in patients with gastric neuroendocrine carcinoma
by: ZHANG Rihong, GUO Yu, LIANG Yun, CHEN Luohai, CHEN Jie, WANG Wei
Published: (2022-09-01)

Functions of Exogenous RUNX2 in Giant Cell Tumor of Bone In Vitro
by: Yuan‐han Jin, et al.
Published: (2020-04-01)

Prognostic Value of Vimentin in Triple Negative Breast Cancer Patients Depends on Chemotherapy Regimen and p53 Mutant Expression
by: Purwanto I, et al.
Published: (2023-07-01)

Transcription Factors Runx1 and Runx3 Suppress Keratin Expression in Undifferentiated Keratinocytes
by: Eisaku Ogawa, et al.
Published: (2022-09-01)

Clinical Outcome of Primary Gastric Lymphoma Treated with Chemotherapy Alone or Surgery Followed by Chemotherapy
by: Ming-Chih Chang, et al.
Published: (2006-01-01)

Perioperative chemotherapy for gastric cancer: the current state
by: V K Lyadov, et al.
Published: (2018-06-01)

Safety and preliminary results of perioperative chemotherapy and hyperthermic intraperitoneal chemotherapy (HIPEC) for high-risk gastric cancer patients
by: Costa Wilson L, et al.
Published: (2012-09-01)