The Circadian Axis and Cardiometabolic Syndrome
Circadian rhythm refers to the daily physiologically fluctuating patterns of systemic processes that occur within a circa 24-hour timeframe, independently of external factors. There is evidence that in time, external and internal cycle misalignment leads to severe health consequences, resulting in t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2022-09-01
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| Series: | Journal of Interdisciplinary Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/jim-2022-0017 |
| _version_ | 1811319829951414272 |
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| author | Varga Boglárka Ionescu Cristian Norbert Szabo Monica Iudita Maria |
| author_facet | Varga Boglárka Ionescu Cristian Norbert Szabo Monica Iudita Maria |
| author_sort | Varga Boglárka |
| collection | DOAJ |
| description | Circadian rhythm refers to the daily physiologically fluctuating patterns of systemic processes that occur within a circa 24-hour timeframe, independently of external factors. There is evidence that in time, external and internal cycle misalignment leads to severe health consequences, resulting in the development of cardiometabolic disturbances. Desynchronized hormonal fluctuations along with daily specific macronutrient utilization patterns are also discussed, which by consequence, are all predictors of metabolic syndrome. The aim of this paper is to provide insight on the circadian clock’s organization throughout the human body and to explain the underlying genetic background. By understanding these well-established molecular mechanisms and processes, we believe this paper will provide accuracy regarding the importance of the circadian clock’s integrity and will highlight its role in the etiopathology of cardiometabolic syndrome. |
| first_indexed | 2024-04-13T12:49:22Z |
| format | Article |
| id | doaj.art-77612e89a34c4acb804c7e9fc334c314 |
| institution | Directory Open Access Journal |
| issn | 2501-8132 |
| language | English |
| last_indexed | 2024-04-13T12:49:22Z |
| publishDate | 2022-09-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Journal of Interdisciplinary Medicine |
| spelling | doaj.art-77612e89a34c4acb804c7e9fc334c3142022-12-22T02:46:16ZengSciendoJournal of Interdisciplinary Medicine2501-81322022-09-0173475510.2478/jim-2022-0017The Circadian Axis and Cardiometabolic SyndromeVarga Boglárka0Ionescu Cristian Norbert1Szabo Monica Iudita Maria2Clinic of Diabetology, Emergency County Clinic, Târgu Mureș, Romania“George Emil Palade” University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, Romania“George Emil Palade” University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, RomaniaCircadian rhythm refers to the daily physiologically fluctuating patterns of systemic processes that occur within a circa 24-hour timeframe, independently of external factors. There is evidence that in time, external and internal cycle misalignment leads to severe health consequences, resulting in the development of cardiometabolic disturbances. Desynchronized hormonal fluctuations along with daily specific macronutrient utilization patterns are also discussed, which by consequence, are all predictors of metabolic syndrome. The aim of this paper is to provide insight on the circadian clock’s organization throughout the human body and to explain the underlying genetic background. By understanding these well-established molecular mechanisms and processes, we believe this paper will provide accuracy regarding the importance of the circadian clock’s integrity and will highlight its role in the etiopathology of cardiometabolic syndrome.https://doi.org/10.2478/jim-2022-0017circadian rhythmcardiometabolic syndromediabetesclock genehormonal fluctuation |
| spellingShingle | Varga Boglárka Ionescu Cristian Norbert Szabo Monica Iudita Maria The Circadian Axis and Cardiometabolic Syndrome Journal of Interdisciplinary Medicine circadian rhythm cardiometabolic syndrome diabetes clock gene hormonal fluctuation |
| title | The Circadian Axis and Cardiometabolic Syndrome |
| title_full | The Circadian Axis and Cardiometabolic Syndrome |
| title_fullStr | The Circadian Axis and Cardiometabolic Syndrome |
| title_full_unstemmed | The Circadian Axis and Cardiometabolic Syndrome |
| title_short | The Circadian Axis and Cardiometabolic Syndrome |
| title_sort | circadian axis and cardiometabolic syndrome |
| topic | circadian rhythm cardiometabolic syndrome diabetes clock gene hormonal fluctuation |
| url | https://doi.org/10.2478/jim-2022-0017 |
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