Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil

In vitro susceptibility of the turpentine oil obtained from Pinus pinaster oleoresin was evaluated against three Sudanese clinical isolates of Actinomadura madurae, which is the main causative agent of actinomycetoma. The minimum inhibitory concentrations (MICs) of the oil ranged from 100.3 to 124.8...

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Main Authors: Stojković D., Soković Marina, Glamočlija Jasmina, Džamić Ana, Ristić M., Fahal A., Khalid Sami, Đuić Ivana, Petrović Silvana
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2008-01-01
Series:Archives of Biological Sciences
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2008/0354-46640804697S.pdf
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author Stojković D.
Soković Marina
Glamočlija Jasmina
Džamić Ana
Ristić M.
Fahal A.
Khalid Sami
Đuić Ivana
Petrović Silvana
author_facet Stojković D.
Soković Marina
Glamočlija Jasmina
Džamić Ana
Ristić M.
Fahal A.
Khalid Sami
Đuić Ivana
Petrović Silvana
author_sort Stojković D.
collection DOAJ
description In vitro susceptibility of the turpentine oil obtained from Pinus pinaster oleoresin was evaluated against three Sudanese clinical isolates of Actinomadura madurae, which is the main causative agent of actinomycetoma. The minimum inhibitory concentrations (MICs) of the oil ranged from 100.3 to 124.8 μL/mL, and the minimum microbicidal concentrations (MMCs) were between 100.3 and 150.0 μL/mL. α-Pinene exhibited prominent bioactivity with MICs ranging between 3.3 and 5.0 μL/mL, while its MMC was 10.0 μL/mL against the same clinical isolates. Pinus pinaster turpentine oil and α-pinene might be useful agents in the treatment of mycetoma caused by A. madurae.
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spelling doaj.art-7763279104304f0a8e43b5c34dbe0f972022-12-21T19:12:17ZengUniversity of Belgrade, University of Novi SadArchives of Biological Sciences0354-46642008-01-0160469770110.2298/ABS0804697SSusceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oilStojković D.Soković MarinaGlamočlija JasminaDžamić AnaRistić M.Fahal A.Khalid SamiĐuić IvanaPetrović SilvanaIn vitro susceptibility of the turpentine oil obtained from Pinus pinaster oleoresin was evaluated against three Sudanese clinical isolates of Actinomadura madurae, which is the main causative agent of actinomycetoma. The minimum inhibitory concentrations (MICs) of the oil ranged from 100.3 to 124.8 μL/mL, and the minimum microbicidal concentrations (MMCs) were between 100.3 and 150.0 μL/mL. α-Pinene exhibited prominent bioactivity with MICs ranging between 3.3 and 5.0 μL/mL, while its MMC was 10.0 μL/mL against the same clinical isolates. Pinus pinaster turpentine oil and α-pinene might be useful agents in the treatment of mycetoma caused by A. madurae.http://www.doiserbia.nb.rs/img/doi/0354-4664/2008/0354-46640804697S.pdfActionomycetomaPinus pinasterActinomadura maduraeturpentine oilα-pineneantimicrobial activity
spellingShingle Stojković D.
Soković Marina
Glamočlija Jasmina
Džamić Ana
Ristić M.
Fahal A.
Khalid Sami
Đuić Ivana
Petrović Silvana
Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil
Archives of Biological Sciences
Actionomycetoma
Pinus pinaster
Actinomadura madurae
turpentine oil
α-pinene
antimicrobial activity
title Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil
title_full Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil
title_fullStr Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil
title_full_unstemmed Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil
title_short Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil
title_sort susceptibility of three clinical isolates of actinomodura madurae to α pinene the bioactive agent of pinus pinaster turpentine oil
topic Actionomycetoma
Pinus pinaster
Actinomadura madurae
turpentine oil
α-pinene
antimicrobial activity
url http://www.doiserbia.nb.rs/img/doi/0354-4664/2008/0354-46640804697S.pdf
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