Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil
In vitro susceptibility of the turpentine oil obtained from Pinus pinaster oleoresin was evaluated against three Sudanese clinical isolates of Actinomadura madurae, which is the main causative agent of actinomycetoma. The minimum inhibitory concentrations (MICs) of the oil ranged from 100.3 to 124.8...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
University of Belgrade, University of Novi Sad
2008-01-01
|
Series: | Archives of Biological Sciences |
Subjects: | |
Online Access: | http://www.doiserbia.nb.rs/img/doi/0354-4664/2008/0354-46640804697S.pdf |
_version_ | 1819032211973734400 |
---|---|
author | Stojković D. Soković Marina Glamočlija Jasmina Džamić Ana Ristić M. Fahal A. Khalid Sami Đuić Ivana Petrović Silvana |
author_facet | Stojković D. Soković Marina Glamočlija Jasmina Džamić Ana Ristić M. Fahal A. Khalid Sami Đuić Ivana Petrović Silvana |
author_sort | Stojković D. |
collection | DOAJ |
description | In vitro susceptibility of the turpentine oil obtained from Pinus pinaster oleoresin was evaluated against three Sudanese clinical isolates of Actinomadura madurae, which is the main causative agent of actinomycetoma. The minimum inhibitory concentrations (MICs) of the oil ranged from 100.3 to 124.8 μL/mL, and the minimum microbicidal concentrations (MMCs) were between 100.3 and 150.0 μL/mL. α-Pinene exhibited prominent bioactivity with MICs ranging between 3.3 and 5.0 μL/mL, while its MMC was 10.0 μL/mL against the same clinical isolates. Pinus pinaster turpentine oil and α-pinene might be useful agents in the treatment of mycetoma caused by A. madurae. |
first_indexed | 2024-12-21T06:58:21Z |
format | Article |
id | doaj.art-7763279104304f0a8e43b5c34dbe0f97 |
institution | Directory Open Access Journal |
issn | 0354-4664 |
language | English |
last_indexed | 2024-12-21T06:58:21Z |
publishDate | 2008-01-01 |
publisher | University of Belgrade, University of Novi Sad |
record_format | Article |
series | Archives of Biological Sciences |
spelling | doaj.art-7763279104304f0a8e43b5c34dbe0f972022-12-21T19:12:17ZengUniversity of Belgrade, University of Novi SadArchives of Biological Sciences0354-46642008-01-0160469770110.2298/ABS0804697SSusceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oilStojković D.Soković MarinaGlamočlija JasminaDžamić AnaRistić M.Fahal A.Khalid SamiĐuić IvanaPetrović SilvanaIn vitro susceptibility of the turpentine oil obtained from Pinus pinaster oleoresin was evaluated against three Sudanese clinical isolates of Actinomadura madurae, which is the main causative agent of actinomycetoma. The minimum inhibitory concentrations (MICs) of the oil ranged from 100.3 to 124.8 μL/mL, and the minimum microbicidal concentrations (MMCs) were between 100.3 and 150.0 μL/mL. α-Pinene exhibited prominent bioactivity with MICs ranging between 3.3 and 5.0 μL/mL, while its MMC was 10.0 μL/mL against the same clinical isolates. Pinus pinaster turpentine oil and α-pinene might be useful agents in the treatment of mycetoma caused by A. madurae.http://www.doiserbia.nb.rs/img/doi/0354-4664/2008/0354-46640804697S.pdfActionomycetomaPinus pinasterActinomadura maduraeturpentine oilα-pineneantimicrobial activity |
spellingShingle | Stojković D. Soković Marina Glamočlija Jasmina Džamić Ana Ristić M. Fahal A. Khalid Sami Đuić Ivana Petrović Silvana Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil Archives of Biological Sciences Actionomycetoma Pinus pinaster Actinomadura madurae turpentine oil α-pinene antimicrobial activity |
title | Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil |
title_full | Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil |
title_fullStr | Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil |
title_full_unstemmed | Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil |
title_short | Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil |
title_sort | susceptibility of three clinical isolates of actinomodura madurae to α pinene the bioactive agent of pinus pinaster turpentine oil |
topic | Actionomycetoma Pinus pinaster Actinomadura madurae turpentine oil α-pinene antimicrobial activity |
url | http://www.doiserbia.nb.rs/img/doi/0354-4664/2008/0354-46640804697S.pdf |
work_keys_str_mv | AT stojkovicd susceptibilityofthreeclinicalisolatesofactinomoduramaduraetoapinenethebioactiveagentofpinuspinasterturpentineoil AT sokovicmarina susceptibilityofthreeclinicalisolatesofactinomoduramaduraetoapinenethebioactiveagentofpinuspinasterturpentineoil AT glamoclijajasmina susceptibilityofthreeclinicalisolatesofactinomoduramaduraetoapinenethebioactiveagentofpinuspinasterturpentineoil AT dzamicana susceptibilityofthreeclinicalisolatesofactinomoduramaduraetoapinenethebioactiveagentofpinuspinasterturpentineoil AT risticm susceptibilityofthreeclinicalisolatesofactinomoduramaduraetoapinenethebioactiveagentofpinuspinasterturpentineoil AT fahala susceptibilityofthreeclinicalisolatesofactinomoduramaduraetoapinenethebioactiveagentofpinuspinasterturpentineoil AT khalidsami susceptibilityofthreeclinicalisolatesofactinomoduramaduraetoapinenethebioactiveagentofpinuspinasterturpentineoil AT đuicivana susceptibilityofthreeclinicalisolatesofactinomoduramaduraetoapinenethebioactiveagentofpinuspinasterturpentineoil AT petrovicsilvana susceptibilityofthreeclinicalisolatesofactinomoduramaduraetoapinenethebioactiveagentofpinuspinasterturpentineoil |