MMP14high macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis

MMP14high macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis

Fibrotic hypersensitivity pneumonitis (FHP) is a fatal interstitial pulmonary disease with limited treatment options. Lung macrophages are a heterogeneous cell population that exhibit distinct subsets with divergent functions, playing pivotal roles in the progression of pulmonary fibrosis. However,...

Full description

Bibliographic Details
Main Authors: Dan Peng, Juan Li, Yin Li, Lingling Bai, Anying Xiong, Xiang He, Xiaolan Li, Qin Ran, Lei Zhang, Manling Jiang, Junyi Wang, Elaine Lai-Han Leung, Pingchang Yang, Guoping Li
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Pharmacological Research
Subjects:
Hypersensitivity pneumonitis
MMP14
Macrophage
Exosome
Fibroblast-to-myofibroblast transition
Pulmonary fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661824000148

Internet

http://www.sciencedirect.com/science/article/pii/S1043661824000148

Similar Items