MMP14high macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis

MMP14high macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis

Fibrotic hypersensitivity pneumonitis (FHP) is a fatal interstitial pulmonary disease with limited treatment options. Lung macrophages are a heterogeneous cell population that exhibit distinct subsets with divergent functions, playing pivotal roles in the progression of pulmonary fibrosis. However,...

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Bibliographic Details
Main Authors:	Dan Peng, Juan Li, Yin Li, Lingling Bai, Anying Xiong, Xiang He, Xiaolan Li, Qin Ran, Lei Zhang, Manling Jiang, Junyi Wang, Elaine Lai-Han Leung, Pingchang Yang, Guoping Li
Format:	Article
Language:	English
Published:	Elsevier 2024-02-01
Series:	Pharmacological Research
Subjects:	Hypersensitivity pneumonitis MMP14 Macrophage Exosome Fibroblast-to-myofibroblast transition Pulmonary fibrosis
Online Access:	http://www.sciencedirect.com/science/article/pii/S1043661824000148

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