HPV 16 E5 oncoprotein is expressed in early stage carcinogenesis and can be a target of immunotherapy

HPV 16 E5 oncoprotein is expressed in early stage carcinogenesis and can be a target of immunotherapy

HPV16 persistent infection is a well-known condition that precedes human cancer development. High risk HPV E5 proteins cooperate with E6/E7 oncogenes to promote hyper-proliferation of infected cells leading to possible cancer progression. Thus, presence of E5 viral transcripts could be a key marker...

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Bibliographic Details
Main Authors: Francesca Paolini, Gianfranca Curzio, Marcelo Nazario Cordeiro, Silvia Massa, Luciano Mariani, Fulvia Pimpinelli, Antonio Carlos de Freitas, Rosella Franconi, Aldo Venuti
Format: Article
Language:English
Published: Taylor & Francis Group 2017-02-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
cancer
e5
hpv
hpv transcripts
immunotherapy
therapeutic vaccine
Online Access:http://dx.doi.org/10.1080/21645515.2017.1264777

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