Gentamicin promoted the production of CD4+CD25+ Tregs via the STAT5 signaling pathway in mice sepsis

Gentamicin promoted the production of CD4+CD25+ Tregs via the STAT5 signaling pathway in mice sepsis

Abstract Background Increasing studies have reported that gentamicin (GNT) plays an essential role in sepsis; however, its underlying mechanism is still unclear. In this study, we investigated the mechanism of GNT in sepsis. Results We observed that GNT enhanced survival and alleviated inflammatory...

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Bibliographic Details
Main Authors: Jinfeng Li, Fengdan Xu, Song Li, Mingyu Xie, Ning Li
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Immunology
Subjects:
Neonatal sepsis
Regulatory T cell
Gentamicin
STAT5
Inflammation
Online Access:https://doi.org/10.1186/s12865-022-00521-4

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