Integrating bulk and single-cell RNA sequencing data reveals epithelial-mesenchymal transition molecular subtype and signature to predict prognosis, immunotherapy efficacy, and drug candidates in low-grade gliomas

Integrating bulk and single-cell RNA sequencing data reveals epithelial-mesenchymal transition molecular subtype and signature to predict prognosis, immunotherapy efficacy, and drug candidates in low-grade gliomas

Objective: Epithelial-mesenchymal transition (EMT) is a tightly regulated and dynamic process occurring in both embryonic development and tumor progression. Our study aimed to comprehensively explore the molecular subtypes, immune landscape, and prognostic signature based on EMT-related genes in low...

Full description

Bibliographic Details
Main Authors: Chengcheng Wang, Zheng He
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
low-grade gliomas
Epithelial-mesenchymal transition (EMT)
molecular subtypes
tumor microenvironment
immunotherpapy
signature
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1276466/full

Similar Items

Similar Items