An optimal control model to design strategies for reducing the spread of the Ebola virus disease

In this work, we formulate an epidemiological model for studying the spread of Ebola virus disease in a considered territory. This model includes the effect of various control measures, such as: vaccination, education campaigns, early detection campaigns, increase of sanitary measures in hospital, q...

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Main Authors: Rama Seck, Diène Ngom, Benjamin Ivorra, Ángel M. Ramos
Format: Article
Language:English
Published: AIMS Press 2022-01-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2022082?viewType=HTML
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author Rama Seck
Diène Ngom
Benjamin Ivorra
Ángel M. Ramos
author_facet Rama Seck
Diène Ngom
Benjamin Ivorra
Ángel M. Ramos
author_sort Rama Seck
collection DOAJ
description In this work, we formulate an epidemiological model for studying the spread of Ebola virus disease in a considered territory. This model includes the effect of various control measures, such as: vaccination, education campaigns, early detection campaigns, increase of sanitary measures in hospital, quarantine of infected individuals and restriction of movement between geographical areas. Using optimal control theory, we determine an optimal control strategy which aims to reduce the number of infected individuals, according to some operative restrictions (e.g., economical, logistic, etc.). Furthermore, we study the existence and uniqueness of the optimal control. Finally, we illustrate the interest of the obtained results by considering numerical experiments based on real data.
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spelling doaj.art-7773d600c4c74007984e230b792a68c82022-12-21T20:09:17ZengAIMS PressMathematical Biosciences and Engineering1551-00182022-01-011921746177410.3934/mbe.2022082An optimal control model to design strategies for reducing the spread of the Ebola virus diseaseRama Seck0Diène Ngom1Benjamin Ivorra2Ángel M. Ramos31. Laboratory of Numerical Analysis and Computer Science, Applied Mathematics Section, Gaston Berger University, Saint-Louis, 209-IRD & UMMISCO-UGB, Senegal2. Mathematics and Applications Laboratory, Mathematics Department, Assane Seck University, Bp: 523, Ziguinchor, 209-IRD & UMMISCO-UGB, Senegal3. Interdisciplinary Mathematics Institute, Department of Applied Mathematics and Mathematical Analysis, Complutense University of Madrid, Plaza de Ciencias, 3, 28040 Madrid, Spain3. Interdisciplinary Mathematics Institute, Department of Applied Mathematics and Mathematical Analysis, Complutense University of Madrid, Plaza de Ciencias, 3, 28040 Madrid, SpainIn this work, we formulate an epidemiological model for studying the spread of Ebola virus disease in a considered territory. This model includes the effect of various control measures, such as: vaccination, education campaigns, early detection campaigns, increase of sanitary measures in hospital, quarantine of infected individuals and restriction of movement between geographical areas. Using optimal control theory, we determine an optimal control strategy which aims to reduce the number of infected individuals, according to some operative restrictions (e.g., economical, logistic, etc.). Furthermore, we study the existence and uniqueness of the optimal control. Finally, we illustrate the interest of the obtained results by considering numerical experiments based on real data.https://www.aimspress.com/article/doi/10.3934/mbe.2022082?viewType=HTMLepidemiological modelingoptimal controlebola virus diseasedeterministic models
spellingShingle Rama Seck
Diène Ngom
Benjamin Ivorra
Ángel M. Ramos
An optimal control model to design strategies for reducing the spread of the Ebola virus disease
Mathematical Biosciences and Engineering
epidemiological modeling
optimal control
ebola virus disease
deterministic models
title An optimal control model to design strategies for reducing the spread of the Ebola virus disease
title_full An optimal control model to design strategies for reducing the spread of the Ebola virus disease
title_fullStr An optimal control model to design strategies for reducing the spread of the Ebola virus disease
title_full_unstemmed An optimal control model to design strategies for reducing the spread of the Ebola virus disease
title_short An optimal control model to design strategies for reducing the spread of the Ebola virus disease
title_sort optimal control model to design strategies for reducing the spread of the ebola virus disease
topic epidemiological modeling
optimal control
ebola virus disease
deterministic models
url https://www.aimspress.com/article/doi/10.3934/mbe.2022082?viewType=HTML
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