Can Non-Invasive Spectrophotometric Hemoglobin Replace Laboratory Hemoglobin Concentrations for Preoperative Anemia Screening? A Diagnostic Test Accuracy Study
Preoperative assessment of hemoglobin concentration in blood is important to diagnose anemia. The primary aim of this prospective diagnostic test accuracy study was to monitor non-invasive spectrophotometric hemoglobin (SpHb, g/dL) concentrations among adults prior to elective surgery and to investi...
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MDPI AG
2023-09-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/17/5733 |
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| author | Maryam Alwabari Fatimah Alhamad Fatimah Alsahaf Fatima Al Amer Fatma Alniniya Imran Alherz Nawal Omer Abdulaziz Bushehab Khaled Yassen |
| author_facet | Maryam Alwabari Fatimah Alhamad Fatimah Alsahaf Fatima Al Amer Fatma Alniniya Imran Alherz Nawal Omer Abdulaziz Bushehab Khaled Yassen |
| author_sort | Maryam Alwabari |
| collection | DOAJ |
| description | Preoperative assessment of hemoglobin concentration in blood is important to diagnose anemia. The primary aim of this prospective diagnostic test accuracy study was to monitor non-invasive spectrophotometric hemoglobin (SpHb, g/dL) concentrations among adults prior to elective surgery and to investigate the correlation and agreement of SpHb with laboratory hemoglobin (Hb, g/dl). A secondary aim was to identify the anemia cut-off values for SpHb based on the World Health Organization (WHO) definitions for anemia. This study included 151 consecutive patients (age ≥ 18 year) presenting for preoperative evaluation prior to scheduled elective general or orthopedic surgery. Results identified the mean ± SD of SpHb at 11.43 ± 2.01 g/dL, which underestimated the mean laboratory Hb (12.64 ± 2.29 g/dL, <i>p</i> < 0.001). A bias mean difference (SpHb–Hb) of −1.21 g/dL, with a SD of 1.76, was reported. This bias (SpHb–Hb) was inversely correlated with the mean Hb concentrations. A positive correlation existed between SpHb and Hb, with a good degree of reliability and a significant Intra Class Correlation (ICC). SpHb diagnosed anemia in 32.3% and 60.3% of males and females, respectively. The SpHb cut-off values to identify anemia were 11.3 and 10.2 g/dL for males and females, respectively, with a sensitivity of 83.3% for males and only 62.9% for females. The specificity for males and females were 81% and 91.3%, respectively. SpHb sensitivity allows for anemia diagnosis among males, but not females. However, the specificity allows SpHb to rule out anemia for both. |
| first_indexed | 2024-03-10T23:19:31Z |
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| institution | Directory Open Access Journal |
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| language | English |
| last_indexed | 2024-03-10T23:19:31Z |
| publishDate | 2023-09-01 |
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| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-777726ab7bb944a8811aacaac71f93852023-11-19T08:24:37ZengMDPI AGJournal of Clinical Medicine2077-03832023-09-011217573310.3390/jcm12175733Can Non-Invasive Spectrophotometric Hemoglobin Replace Laboratory Hemoglobin Concentrations for Preoperative Anemia Screening? A Diagnostic Test Accuracy StudyMaryam Alwabari0Fatimah Alhamad1Fatimah Alsahaf2Fatima Al Amer3Fatma Alniniya4Imran Alherz5Nawal Omer6Abdulaziz Bushehab7Khaled Yassen8Anesthesia Department, King Fahad Hospital, Ministry of Health, Hofuf 36441, Al Ahsa, Saudi ArabiaCollege of Medicine, King Faisal University, Hofuf 31983, Al Ahsa, Saudi ArabiaCollege of Medicine, King Faisal University, Hofuf 31983, Al Ahsa, Saudi ArabiaCollege of Medicine, King Faisal University, Hofuf 31983, Al Ahsa, Saudi ArabiaAnesthesia Department, King Fahad Hospital, Ministry of Health, Hofuf 36441, Al Ahsa, Saudi ArabiaAnesthesia Department, King Fahad Hospital, Ministry of Health, Hofuf 36441, Al Ahsa, Saudi ArabiaHereditary Blood Disease Center, Hofuf 36422, Al Ahsa, Saudi ArabiaNursing Services, Hereditary Blood Disease Center, Hofuf 36422, Al Ahsa, Saudi ArabiaAnesthesia Unit, Surgery Department, College of Medicine, King Faisal University, Hofuf 31983, Al Ahsa, Saudi ArabiaPreoperative assessment of hemoglobin concentration in blood is important to diagnose anemia. The primary aim of this prospective diagnostic test accuracy study was to monitor non-invasive spectrophotometric hemoglobin (SpHb, g/dL) concentrations among adults prior to elective surgery and to investigate the correlation and agreement of SpHb with laboratory hemoglobin (Hb, g/dl). A secondary aim was to identify the anemia cut-off values for SpHb based on the World Health Organization (WHO) definitions for anemia. This study included 151 consecutive patients (age ≥ 18 year) presenting for preoperative evaluation prior to scheduled elective general or orthopedic surgery. Results identified the mean ± SD of SpHb at 11.43 ± 2.01 g/dL, which underestimated the mean laboratory Hb (12.64 ± 2.29 g/dL, <i>p</i> < 0.001). A bias mean difference (SpHb–Hb) of −1.21 g/dL, with a SD of 1.76, was reported. This bias (SpHb–Hb) was inversely correlated with the mean Hb concentrations. A positive correlation existed between SpHb and Hb, with a good degree of reliability and a significant Intra Class Correlation (ICC). SpHb diagnosed anemia in 32.3% and 60.3% of males and females, respectively. The SpHb cut-off values to identify anemia were 11.3 and 10.2 g/dL for males and females, respectively, with a sensitivity of 83.3% for males and only 62.9% for females. The specificity for males and females were 81% and 91.3%, respectively. SpHb sensitivity allows for anemia diagnosis among males, but not females. However, the specificity allows SpHb to rule out anemia for both.https://www.mdpi.com/2077-0383/12/17/5733hemoglobinanemiamonitoringnon-invasivepreoperative |
| spellingShingle | Maryam Alwabari Fatimah Alhamad Fatimah Alsahaf Fatima Al Amer Fatma Alniniya Imran Alherz Nawal Omer Abdulaziz Bushehab Khaled Yassen Can Non-Invasive Spectrophotometric Hemoglobin Replace Laboratory Hemoglobin Concentrations for Preoperative Anemia Screening? A Diagnostic Test Accuracy Study Journal of Clinical Medicine hemoglobin anemia monitoring non-invasive preoperative |
| title | Can Non-Invasive Spectrophotometric Hemoglobin Replace Laboratory Hemoglobin Concentrations for Preoperative Anemia Screening? A Diagnostic Test Accuracy Study |
| title_full | Can Non-Invasive Spectrophotometric Hemoglobin Replace Laboratory Hemoglobin Concentrations for Preoperative Anemia Screening? A Diagnostic Test Accuracy Study |
| title_fullStr | Can Non-Invasive Spectrophotometric Hemoglobin Replace Laboratory Hemoglobin Concentrations for Preoperative Anemia Screening? A Diagnostic Test Accuracy Study |
| title_full_unstemmed | Can Non-Invasive Spectrophotometric Hemoglobin Replace Laboratory Hemoglobin Concentrations for Preoperative Anemia Screening? A Diagnostic Test Accuracy Study |
| title_short | Can Non-Invasive Spectrophotometric Hemoglobin Replace Laboratory Hemoglobin Concentrations for Preoperative Anemia Screening? A Diagnostic Test Accuracy Study |
| title_sort | can non invasive spectrophotometric hemoglobin replace laboratory hemoglobin concentrations for preoperative anemia screening a diagnostic test accuracy study |
| topic | hemoglobin anemia monitoring non-invasive preoperative |
| url | https://www.mdpi.com/2077-0383/12/17/5733 |
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