The value of added opposed/in phase MRI sequences in characterization of the focal vertebral bone marrow lesions in oncology patients
Objective: This study aimed to evaluate the value of added opposed/in phase MRI sequences with signal intensity ratio (SIR) calculations in differentiation malignant and benign vertebral focal marrow lesions in oncology patients. Patients and methods: From January 2013 to December 2014, a total of 5...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2015-09-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0378603X15001060 |
| _version_ | 1818361499422294016 |
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| author | Hoda A. El-Kareem A. El-Samie Hosny Sayed A. El-Ghany |
| author_facet | Hoda A. El-Kareem A. El-Samie Hosny Sayed A. El-Ghany |
| author_sort | Hoda A. El-Kareem A. El-Samie |
| collection | DOAJ |
| description | Objective: This study aimed to evaluate the value of added opposed/in phase MRI sequences with signal intensity ratio (SIR) calculations in differentiation malignant and benign vertebral focal marrow lesions in oncology patients.
Patients and methods: From January 2013 to December 2014, a total of 50 oncology patients with 63 focal spinal bone marrow lesions underwent MRI examination with added opposed/in-phase sequences. A computation of SIR of the marrow on the opposed phase to signal intensity measured on the in-phase images was made.
Results: The examined 50 oncology patients showed 63 focal lesions, 39 proved to be malignant and 24 diagnosed as benign. The majority of malignant lesions (32/39) showed persistence of the high signals at the opposed phase sequences while signal loss was noted on all benign lesions. SIR values were ranged between 1.1 and 2.6 in malignant lesions while it ranged from 0.47 to 0.9 in benign lesions; when a SIR of 1 as a cutoff was chosen, it showed high sensitivity and specificity (96.8% and 93.65% respectively).
Conclusion: The added opposed/in phase MRI sequences with SIR cut-off value of 1, were proved to be a non-invasive sensitive tool to differentiate between malignant and benign lesions in oncology patients. |
| first_indexed | 2024-12-13T21:17:39Z |
| format | Article |
| id | doaj.art-777a2b09f6154a799406480598680c15 |
| institution | Directory Open Access Journal |
| issn | 0378-603X |
| language | English |
| last_indexed | 2024-12-13T21:17:39Z |
| publishDate | 2015-09-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-777a2b09f6154a799406480598680c152022-12-21T23:31:12ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2015-09-0146372773210.1016/j.ejrnm.2015.05.004The value of added opposed/in phase MRI sequences in characterization of the focal vertebral bone marrow lesions in oncology patientsHoda A. El-Kareem A. El-Samie0Hosny Sayed A. El-Ghany1South Valley University, Departments of Radiology, EgyptEl Minia University, Departments of Radiology, EgyptObjective: This study aimed to evaluate the value of added opposed/in phase MRI sequences with signal intensity ratio (SIR) calculations in differentiation malignant and benign vertebral focal marrow lesions in oncology patients. Patients and methods: From January 2013 to December 2014, a total of 50 oncology patients with 63 focal spinal bone marrow lesions underwent MRI examination with added opposed/in-phase sequences. A computation of SIR of the marrow on the opposed phase to signal intensity measured on the in-phase images was made. Results: The examined 50 oncology patients showed 63 focal lesions, 39 proved to be malignant and 24 diagnosed as benign. The majority of malignant lesions (32/39) showed persistence of the high signals at the opposed phase sequences while signal loss was noted on all benign lesions. SIR values were ranged between 1.1 and 2.6 in malignant lesions while it ranged from 0.47 to 0.9 in benign lesions; when a SIR of 1 as a cutoff was chosen, it showed high sensitivity and specificity (96.8% and 93.65% respectively). Conclusion: The added opposed/in phase MRI sequences with SIR cut-off value of 1, were proved to be a non-invasive sensitive tool to differentiate between malignant and benign lesions in oncology patients.http://www.sciencedirect.com/science/article/pii/S0378603X15001060Opposed/in phaseFocal marrow lesionsOncology patients |
| spellingShingle | Hoda A. El-Kareem A. El-Samie Hosny Sayed A. El-Ghany The value of added opposed/in phase MRI sequences in characterization of the focal vertebral bone marrow lesions in oncology patients The Egyptian Journal of Radiology and Nuclear Medicine Opposed/in phase Focal marrow lesions Oncology patients |
| title | The value of added opposed/in phase MRI sequences in characterization of the focal vertebral bone marrow lesions in oncology patients |
| title_full | The value of added opposed/in phase MRI sequences in characterization of the focal vertebral bone marrow lesions in oncology patients |
| title_fullStr | The value of added opposed/in phase MRI sequences in characterization of the focal vertebral bone marrow lesions in oncology patients |
| title_full_unstemmed | The value of added opposed/in phase MRI sequences in characterization of the focal vertebral bone marrow lesions in oncology patients |
| title_short | The value of added opposed/in phase MRI sequences in characterization of the focal vertebral bone marrow lesions in oncology patients |
| title_sort | value of added opposed in phase mri sequences in characterization of the focal vertebral bone marrow lesions in oncology patients |
| topic | Opposed/in phase Focal marrow lesions Oncology patients |
| url | http://www.sciencedirect.com/science/article/pii/S0378603X15001060 |
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