THE INDICES DYNAMICS OF PLATELET POOL AND THE LEVEL OF TGF-Β<sub>1</sub> IN DIFFERENT FORMS OF ACUTE PANCREATITIS

The results of study of quantitative functional characteristics of platelets are shown in patients with acute pancreatitis. The patients (57 people) with acute pancreatitis were examined: 40 patients had a mild clinical course of acute pancreatitis and 40 patients had a severe clinical course of acu...

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Main Authors: E. N. Smolina, O. V. Pridantseva, M. B. Kadinskaya, O. V. Galkina, E. O. Bogdanova
Format: Article
Language:Russian
Published: Pavlov First Saint Petersburg State Medical University 2018-01-01
Series:Вестник хирургии имени И.И. Грекова
Subjects:
Online Access:https://www.vestnik-grekova.ru/jour/article/view/714
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author E. N. Smolina
O. V. Pridantseva
M. B. Kadinskaya
O. V. Galkina
E. O. Bogdanova
author_facet E. N. Smolina
O. V. Pridantseva
M. B. Kadinskaya
O. V. Galkina
E. O. Bogdanova
author_sort E. N. Smolina
collection DOAJ
description The results of study of quantitative functional characteristics of platelets are shown in patients with acute pancreatitis. The patients (57 people) with acute pancreatitis were examined: 40 patients had a mild clinical course of acute pancreatitis and 40 patients had a severe clinical course of acute pancreatitis. The circular functional mass of platelets and the level of TGF-β1 were determined in dynamics in patients with acute destructive pancreatitis. A correlated analysis was made among the results obtained by means of laboratory and instrumental examinations and clinical course of acute pancreatitis. It was found, that the increase of TGF-β1 and circular functional mass of platelets in the course of several days was really a good prognostic factor of clinical course of acute pancreatitis. The data obtained showed that the changes of indices of quantitative and functional characteristics of platelets are the important pathogenetic criterion of prognosis for severity of clinical course of acute pancreatitis.
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spelling doaj.art-777b19a52e084320adb2cfd1d702f8e02023-03-13T08:09:15ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252018-01-01172307307510.24884/0042-4625-2013-172-3-073-075713THE INDICES DYNAMICS OF PLATELET POOL AND THE LEVEL OF TGF-Β<sub>1</sub> IN DIFFERENT FORMS OF ACUTE PANCREATITISE. N. Smolina0O. V. Pridantseva1M. B. Kadinskaya2O. V. Galkina3E. O. Bogdanova4State Pavlov Medical UniversityState Pavlov Medical UniversityState Pavlov Medical UniversityState Pavlov Medical UniversityState Pavlov Medical UniversityThe results of study of quantitative functional characteristics of platelets are shown in patients with acute pancreatitis. The patients (57 people) with acute pancreatitis were examined: 40 patients had a mild clinical course of acute pancreatitis and 40 patients had a severe clinical course of acute pancreatitis. The circular functional mass of platelets and the level of TGF-β1 were determined in dynamics in patients with acute destructive pancreatitis. A correlated analysis was made among the results obtained by means of laboratory and instrumental examinations and clinical course of acute pancreatitis. It was found, that the increase of TGF-β1 and circular functional mass of platelets in the course of several days was really a good prognostic factor of clinical course of acute pancreatitis. The data obtained showed that the changes of indices of quantitative and functional characteristics of platelets are the important pathogenetic criterion of prognosis for severity of clinical course of acute pancreatitis.https://www.vestnik-grekova.ru/jour/article/view/714острый панкреатиттромбоцитыбета-трансформирующий фактор ростаacute pancreatitisplateletstgf-beta factor
spellingShingle E. N. Smolina
O. V. Pridantseva
M. B. Kadinskaya
O. V. Galkina
E. O. Bogdanova
THE INDICES DYNAMICS OF PLATELET POOL AND THE LEVEL OF TGF-Β<sub>1</sub> IN DIFFERENT FORMS OF ACUTE PANCREATITIS
Вестник хирургии имени И.И. Грекова
острый панкреатит
тромбоциты
бета-трансформирующий фактор роста
acute pancreatitis
platelets
tgf-beta factor
title THE INDICES DYNAMICS OF PLATELET POOL AND THE LEVEL OF TGF-Β<sub>1</sub> IN DIFFERENT FORMS OF ACUTE PANCREATITIS
title_full THE INDICES DYNAMICS OF PLATELET POOL AND THE LEVEL OF TGF-Β<sub>1</sub> IN DIFFERENT FORMS OF ACUTE PANCREATITIS
title_fullStr THE INDICES DYNAMICS OF PLATELET POOL AND THE LEVEL OF TGF-Β<sub>1</sub> IN DIFFERENT FORMS OF ACUTE PANCREATITIS
title_full_unstemmed THE INDICES DYNAMICS OF PLATELET POOL AND THE LEVEL OF TGF-Β<sub>1</sub> IN DIFFERENT FORMS OF ACUTE PANCREATITIS
title_short THE INDICES DYNAMICS OF PLATELET POOL AND THE LEVEL OF TGF-Β<sub>1</sub> IN DIFFERENT FORMS OF ACUTE PANCREATITIS
title_sort indices dynamics of platelet pool and the level of tgf β sub 1 sub in different forms of acute pancreatitis
topic острый панкреатит
тромбоциты
бета-трансформирующий фактор роста
acute pancreatitis
platelets
tgf-beta factor
url https://www.vestnik-grekova.ru/jour/article/view/714
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