Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiation
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has devastated global public health systems and economies, with over 52 million people infected, millions of jobs and businesses lost, and more than 1 million deaths recorded to date. Contact with surfaces contaminate...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-020-79600-8 |
| _version_ | 1818749662262198272 |
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| author | Nadia Storm Lindsay G. A. McKay Sierra N. Downs Rebecca I. Johnson Dagnachew Birru Marc de Samber Walter Willaert Giovanni Cennini Anthony Griffiths |
| author_facet | Nadia Storm Lindsay G. A. McKay Sierra N. Downs Rebecca I. Johnson Dagnachew Birru Marc de Samber Walter Willaert Giovanni Cennini Anthony Griffiths |
| author_sort | Nadia Storm |
| collection | DOAJ |
| description | Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has devastated global public health systems and economies, with over 52 million people infected, millions of jobs and businesses lost, and more than 1 million deaths recorded to date. Contact with surfaces contaminated with droplets generated by infected persons through exhaling, talking, coughing and sneezing is a major driver of SARS-CoV-2 transmission, with the virus being able to survive on surfaces for extended periods of time. To interrupt these chains of transmission, there is an urgent need for devices that can be deployed to inactivate the virus on both recently and existing contaminated surfaces. Here, we describe the inactivation of SARS-CoV-2 in both wet and dry format using radiation generated by a commercially available Signify ultraviolet (UV)-C light source at 254 nm. We show that for contaminated surfaces, only seconds of exposure is required for complete inactivation, allowing for easy implementation in decontamination workflows. |
| first_indexed | 2024-12-18T04:07:20Z |
| format | Article |
| id | doaj.art-777b21565801462a9a2bbe7e08aecb1c |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-18T04:07:20Z |
| publishDate | 2020-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-777b21565801462a9a2bbe7e08aecb1c2022-12-21T21:21:34ZengNature PortfolioScientific Reports2045-23222020-12-011011510.1038/s41598-020-79600-8Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiationNadia Storm0Lindsay G. A. McKay1Sierra N. Downs2Rebecca I. Johnson3Dagnachew Birru4Marc de Samber5Walter Willaert6Giovanni Cennini7Anthony Griffiths8National Emerging Infectious Diseases Laboratories, Boston University School of MedicineNational Emerging Infectious Diseases Laboratories, Boston University School of MedicineNational Emerging Infectious Diseases Laboratories, Boston University School of MedicineNational Emerging Infectious Diseases Laboratories, Boston University School of MedicineSignify ResearchSignify ResearchSignify ResearchSignify ResearchNational Emerging Infectious Diseases Laboratories, Boston University School of MedicineAbstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has devastated global public health systems and economies, with over 52 million people infected, millions of jobs and businesses lost, and more than 1 million deaths recorded to date. Contact with surfaces contaminated with droplets generated by infected persons through exhaling, talking, coughing and sneezing is a major driver of SARS-CoV-2 transmission, with the virus being able to survive on surfaces for extended periods of time. To interrupt these chains of transmission, there is an urgent need for devices that can be deployed to inactivate the virus on both recently and existing contaminated surfaces. Here, we describe the inactivation of SARS-CoV-2 in both wet and dry format using radiation generated by a commercially available Signify ultraviolet (UV)-C light source at 254 nm. We show that for contaminated surfaces, only seconds of exposure is required for complete inactivation, allowing for easy implementation in decontamination workflows.https://doi.org/10.1038/s41598-020-79600-8 |
| spellingShingle | Nadia Storm Lindsay G. A. McKay Sierra N. Downs Rebecca I. Johnson Dagnachew Birru Marc de Samber Walter Willaert Giovanni Cennini Anthony Griffiths Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiation Scientific Reports |
| title | Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiation |
| title_full | Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiation |
| title_fullStr | Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiation |
| title_full_unstemmed | Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiation |
| title_short | Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiation |
| title_sort | rapid and complete inactivation of sars cov 2 by ultraviolet c irradiation |
| url | https://doi.org/10.1038/s41598-020-79600-8 |
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