Yomogin, Isolated from <i>Artemisia iwayomogi</i>, Inhibits Neuroinflammation Stimulated by Lipopolysaccharide via Regulating MAPK Pathway

Yomogin, Isolated from <i>Artemisia iwayomogi</i>, Inhibits Neuroinflammation Stimulated by Lipopolysaccharide via Regulating MAPK Pathway

Neuroinflammation causes various neurological disorders, including depression and neurodegenerative diseases. Therefore, regulation of neuroinflammation is a promising therapeutic strategy for inflammation-related neurological disorders. This study aimed to investigate whether yomogin, isolated from...

Full description

Bibliographic Details
Main Authors:	Jin Hee Kim, In Gyoung Ju, Namkwon Kim, Eugene Huh, So-Ri Son, Joon Pyo Hong, Yujin Choi, Dae Sik Jang, Myung Sook Oh
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Series:	Antioxidants
Subjects:	yomogin neuroinflammation p38 mitogen-activated protein kinases JNK mitogen-activated protein kinases ERK extracellular signal-regulated kinase <i>Artemisia iwayomogi</i>
Online Access:	https://www.mdpi.com/2076-3921/12/1/106

Similar Items

Chemical Constituents from the Aerial Parts of <i>Artemisia iwayomogi</i> and Their Anti-Neuroinflammatory Activities
by: So-Ri Son, et al.
Published: (2022-07-01)

Mitogen-activated protein/extracellular signal-regulated kinase kinase 1act/tubulin interaction is an important determinant of mitotic stability in cultured HT1080 human fibrosarcoma cells.
by: Cao, Jia-ning, et al.
Published: (2010)

MAPK immunoreactivity in streptozotocin-induced diabetic rat testis
by: Yelız Bozdemır Donmez, et al.
Published: (2014-10-01)

In vitro and in vivo anti-aging effects of compounds isolated from Artemisia iwayomogi
by: Kyung Young Kim, et al.
Published: (2019-12-01)

The Solanum chacoense Fertilization-Related Kinase 3 (ScFRK3) is involved in male and female gametophyte development
by: Caroline Daigle, et al.
Published: (2019-05-01)

Atrial ERK1/2 activation in the embryo leads to incomplete Septal closure: a novel mouse model of atrial Septal defect
by: Che-Chung Yeh, et al.
Published: (2017-11-01)

Inducible nitric oxide synthase regulates macrophage polarization via the MAPK signals in concanavalin A‐induced hepatitis
by: Xiaoying Yao, et al.
Published: (2022-07-01)

Analysis of pain markers and epidural fibrosis caused by repeated spinal surgery in Sprague–Dawley rats
by: Meiling Quan, et al.
Published: (2021-01-01)

Gαi3-dependent inhibition of JNK activity on intracellular membranes
by: Guillaume eBastin, et al.
Published: (2015-09-01)

The Clinical Application of Pulsed Radiofrequency Induces Inflammatory Pain via MAPKs Activation: A Novel Hint for Pulsed Radiofrequency Treatment
by: Feng-Yen Lin, et al.
Published: (2021-11-01)

Luteolin, quercetin, genistein and quercetagetin inhibit the effects of lipopolysaccharide obtained from Porphyromonas gingivalis in H9c2 cardiomyoblasts
by: Gloria Gutiérrez-Venegas, et al.
Published: (2017-09-01)

Effects of Selenium in the MAPK Signaling Cascade
by: Nadereh Rashtchizadeh, et al.
Published: (2015-09-01)

Ceramide regulation of nuclear protein imports⃞
by: Randolph S. Faustino, et al.
Published: (2008-03-01)

The role of lipolysis in mediating the proinflammatory effects of very low density lipoproteins in mouse peritoneal macrophages
by: Viswanathan Saraswathi, et al.
Published: (2006-07-01)

Antibacterial compounds against fish pathogenic bacteria from a combined extract of Angelica gigas and Artemisia iwayomogi and their quantitative analyses
by: Jae-Woong Lim, et al.
Published: (2021-10-01)

Epistatic Relationship between <i>MGV1</i> and <i>TRI6</i> in the Regulation of Biosynthetic Gene Clusters in <i>Fusarium graminearum</i>
by: Kristina Shostak, et al.
Published: (2023-08-01)

Protein Kinases as Drug Development Targets for Heart Disease Therapy
by: Alison L. Müller, et al.
Published: (2010-07-01)

Alantolactone inhibits proliferation, metastasis and promotes apoptosis of human osteosarcoma cells by suppressing Wnt/β-catenin and MAPKs signaling pathways
by: Chunmei Yang, et al.
Published: (2022-03-01)

A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse
by: Min Sung Gee, et al.
Published: (2020-04-01)

Wheat Bran Extract Regulates Mast Cell-Mediated Allergic Responses In Vitro and In Vivo
by: Jae Yeon Lee, et al.
Published: (2020-09-01)

Suppressive Effect of Fraxetin on Adipogenesis and Reactive Oxygen Species Production in 3T3-L1 Cells by Regulating MAPK Signaling Pathways
by: Woonghee Lee, et al.
Published: (2022-09-01)

MAPK Signaling Pathways in Hepatic Ischemia/Reperfusion Injury
by: Yu B, et al.
Published: (2023-03-01)

The Molecular Biology and Treatment of Malignant Melanoma with BRAFV600 Mutations
by: Michael P. Mullane
Published: (2014-01-01)

Losmapimod Protected Epileptic Rats From Hippocampal Neuron Damage Through Inhibition of the MAPK Pathway
by: Min Li, et al.
Published: (2019-06-01)

The Cell Wall Integrity Signaling Pathway and Its Involvement in Secondary Metabolite Production
by: Vito Valiante
Published: (2017-12-01)

Control of host cell phosphorylation by Legionella pneumophila
by: Eva eHaenssler, et al.
Published: (2011-04-01)

Eight Weeks of Swimming Training and CBD Oil Consumption Downregulates the Expression of MAPK and PPARα Genes in the Heart Tissue of Myocardial Infarction Rats
by: Ali Mohammadnia, et al.
Published: (2021-09-01)

Pharmacological implications from the adhesion-induced signaling profiles in cultured human retinal pigment epithelial cells
by: Wen-Chuan Wu, et al.
Published: (2014-01-01)

<i>Combretum quadrangulare</i> Extract Attenuates Atopic Dermatitis-Like Skin Lesions through Modulation of MAPK Signaling in BALB/c Mice
by: Ju-Hyoung Park, et al.
Published: (2020-04-01)

Wound-Healing and Skin-Moisturizing Effects of <i>Sasa veitchii</i> Extract
by: Nobutomo Ikarashi, et al.
Published: (2021-06-01)

KCl Mediates K+ Channel-Activated Mitogen-Activated Protein Kinases Signaling in Wound Healing
by: Jung Hee Shim, et al.
Published: (2015-01-01)

Molecular Mechanisms of Glucose Fluctuations on Diabetic Complications
by: Zhen-Ye Zhang, et al.
Published: (2019-09-01)

An Anthocyanin-Enriched Extract from <i>Vaccinium uliginosum</i> Improves Signs of Skin Aging in UVB-Induced Photodamage
by: Kyungae Jo, et al.
Published: (2020-09-01)

CXCL3 positively regulates adipogenic differentiation
by: Joji Kusuyama, et al.
Published: (2016-10-01)

Ammoxetine attenuates diabetic neuropathic pain through inhibiting microglial activation and neuroinflammation in the spinal cord
by: Ting-Ting Zhang, et al.
Published: (2018-06-01)

Protective Effects on Neuronal SH-SY5Y Cells and Antioxidant Activity of Enzymatic Hydrolyzate from Silkworms Fed the Leaves of <i>Cudrania tricuspidata</i>
by: Gyu-Mi An, et al.
Published: (2024-02-01)

Inhibition of Casein Kinase 2 Protects Oligodendrocytes From Excitotoxicity by Attenuating JNK/p53 Signaling Cascade
by: Manuel Canedo-Antelo, et al.
Published: (2018-09-01)

MicroRNA-370-5p inhibits pigmentation and cell proliferation by downregulating mitogen-activated protein kinase kinase kinase 8 expression in sheep melanocytes
by: Kai-yuan JI, et al.
Published: (2023-04-01)

ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK
by: Sergey Filippov, et al.
Published: (2013-08-01)

Chrysosplenol <span style="font-variant: small-caps">d</span>, a Flavonol from <i>Artemisia annua</i>, Induces ERK1/2-Mediated Apoptosis in Triple Negative Human Breast Cancer Cells
by: Sophia J. Lang, et al.
Published: (2020-06-01)