Suppressing of Src–Hic-5–JNK–AKT Signaling Reduced GAPDH Expression for Preventing the Progression of HuCCT1 Cholangiocarcinoma

Suppressing of Src–Hic-5–JNK–AKT Signaling Reduced GAPDH Expression for Preventing the Progression of HuCCT1 Cholangiocarcinoma

Cholangiocarcinoma (CCA) is a malignant neoplasm of the bile ducts, being the second most common type of cancer in the liver, and most patients are diagnosed at a late stage with poor prognosis. Targeted therapy aiming at receptors tyrosine kinases (RTKs) such as c-Met or EGFR have been developed bu...

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Bibliographic Details
Main Authors: Wen-Sheng Wu, Rui-Fang Chen, Chuan-Chu Cheng, Jia-Ling Wei, Chen-Fang Lin, Ren-In You, Yen-Chang Chen, Ming-Che Lee, Yen-Cheng Chen
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
cholangiocarcinoma
HuCCT1
TFK1
hydrogen peroxide clone-5
Src nonreceptor tyrosine kinase
glyceraldehyde-3-phosphate dehydrogenase
Online Access:https://www.mdpi.com/1999-4923/14/12/2698

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https://www.mdpi.com/1999-4923/14/12/2698

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