X-ray Structures and Computational Studies of Two Bioactive 2-(Adamantane-1-carbonyl)-<i>N</i>-substituted Hydrazine-1-carbothioamides

X-ray Structures and Computational Studies of Two Bioactive 2-(Adamantane-1-carbonyl)-<i>N</i>-substituted Hydrazine-1-carbothioamides

Two biologically active adamantane-linked hydrazine-1-carbothioamide derivatives, namely 2-(adamantane-1-carbonyl)-<i>N</i>-(<i>tert</i>-butyl)hydrazine-1-carbothioamide) <b>1</b> and 2-(adamantane-1-carbonyl)-<i>N</i>-cyclohexylhydrazine-1-carbothioam...

Full description

Bibliographic Details
Main Authors:	Lamya H. Al-Wahaibi, Kowsalya Alagappan, Olivier Blacque, Ahmed A. B. Mohamed, Hanan M. Hassan, María Judith Percino, Ali A. El-Emam, Subbiah Thamotharan
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Series:	Molecules
Subjects:	adamantane hydrazine-1-carbothioamide Hirshfeld surface CLP–Pixel QTAIM molecular docking
Online Access:	https://www.mdpi.com/1420-3049/27/23/8425

Similar Items

Weak noncovalent interactions in two positional isomers of acrylonitrile derivatives: inputs from PIXEL energy, Hirshfeld surface and QTAIM analyses
by: M. Judith Percino, et al.
Published: (2023-06-01)

Synthesis, Antimicrobial and Hypoglycemic Activities of Novel N-(1-Adamantyl)carbothioamide Derivatives
by: Ebtehal S. Al-Abdullah, et al.
Published: (2015-05-01)

Functionalized Oxoindolin Hydrazine Carbothioamide Derivatives as Highly Potent Inhibitors of Nucleoside Triphosphate Diphosphohydrolases
by: Saira Afzal, et al.
Published: (2020-11-01)

A Practical Hydrazine-Carbothioamide-Based Fluorescent Probe for the Detection of Zn<sup>2+</sup>: Applications to Paper Strip, Zebrafish and Water Samples
by: Boeon Suh, et al.
Published: (2022-01-01)

Editorial: Experimental and theoretical investigation of non-covalent interactions in potential bioactive compounds
by: Subbiah Thamotharan, et al.
Published: (2023-11-01)

Weak Noncovalent Interactions in Three Closely Related Adamantane-Linked 1,2,4-Triazole <i>N</i>-Mannich Bases: Insights from Energy Frameworks, Hirshfeld Surface Analysis, <i>In Silico</i> 11β-HSD1 Molecular Docking and ADMET Prediction
by: Lamya H. Al-Wahaibi, et al.
Published: (2022-10-01)

Synthesis and Structure Insights of Two Novel Broad-Spectrum Antibacterial Candidates Based on (<i>E</i>)-<i>N</i>′-[(Heteroaryl)methylene]adamantane-1-carbohydrazides
by: Lamya H. Al-Wahaibi, et al.
Published: (2020-04-01)

Synthesis, physical-chemical properties, antimicrobial and antifungal activity of some 2-(2-((5-(adamantane-1-yl)-4-R-1,2,4-triazole-3-yl)thio)acetyl)-N-R1–hydrazine-carbothioamides
by: V. M. Odyntsova, et al.
Published: (2017-12-01)

SYNTHESIS AND CHARACTERIZATION OF [(5-MERCAPTO-1,3,4-OXADIAZOL-2-YL)ARYL]-3,5-DIARYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOTHIOAMIDES
by: Zinaida Ribkovskaia, et al.
Published: (2011-06-01)

Structural Insights and Docking Analysis of Adamantane-Linked 1,2,4-Triazole Derivatives as Potential 11β-HSD1 Inhibitors
by: Doaa A. Osman, et al.
Published: (2021-09-01)

70th Anniversary of the First Synthesis of Adamantane
by: Škorić, I., et al.
Published: (2011-12-01)

Synthesis, characterization, DFT, cytotoxicity evaluation and molecular docking of a new carbothioamide ligand and its coordination compounds
by: Nasser Mohammed Hosny, et al.
Published: (2023-01-01)

Adamantan, ugradbena jedinica u makrocikličkim sustavima
by: Vujasinović, I., et al.
Published: (2007-03-01)

1-(3-Isoselenocyanatopropyl)adamantane
by: Dmitry Pitushkin, et al.
Published: (2023-05-01)

Evaluation of inhibitive corrosion potential of symmetrical hydrazine derivatives containing nitrophenyl moiety in 1M HCl for C38 steel: experimental and theoretical studies
by: Zouhair Lakbaibi, et al.
Published: (2022-03-01)

2-[(2-Isopropyl-5-methylphenoxy)acetyl]-N-phenylhydrazine Carbothioamide
by: Abdullah Mohamed Asiri
Published: (2003-02-01)

Synthesis of 1,2-Disubstituted Adamantane Derivatives by Construction of the Adamantane Framework
by: Matthew Todd, et al.
Published: (2023-11-01)

Crystal structures and Hirshfeld surface analysis of 2-(adamantan-1-yl)-5-(4-fluorophenyl)-1,3,4-oxadiazole and 2-(adamantan-1-yl)-5-(4-chlorophenyl)-1,3,4-oxadiazole
by: Lamya H. Al-Wahaibi, et al.
Published: (2019-05-01)

Structure and growth kinetics of films of adamantane in a glow discharge
by: Alexandr M Shterenberg, et al.
Published: (2012-09-01)

Crystal structure of (E)-4-(acetoxyimino)-N-allyl-3-isopropyl-2,6-diphenylpiperidine-1-carbothioamide
by: T. Mohandas, et al.
Published: (2015-08-01)

Theoretical Study on Molecular Structure and Electronic Properties of New 1,3-Diaza-adamantan-6-ones Derivatives
by: Haithem Abdulhasan, et al.
Published: (2020-05-01)

N-(Pyrazin-2-yl)adamantane-1-carboxamide
by: Błażej Dziuk, et al.
Published: (2016-08-01)

Synthesis and crystal structure of 3-(adamantan-1-yl)-4-(2-bromo-4-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione
by: Alaa S. Abdelrazeq, et al.
Published: (2020-02-01)

Synthesis and Bioactivity of Thiosemicarbazones Containing Adamantane Skeletons
by: Van Hien Pham, et al.
Published: (2020-01-01)

Crystallographic and Theoretical Exploration of Weak Hydrogen Bonds in Arylmethyl N′‑(adamantan-1-yl)piperidine-1-carbothioimidates and Molecular Docking Analysis
by: Aamal A. Al-Mutairi, et al.
Published: (2021-10-01)

Tribenzamidomethyl Hydrazine
by: Emil Popovski, et al.
Published: (2010-12-01)

Crystal structure of (E)-2-[3-(tert-butyl)-2-hydroxybenzylidene]-N-cyclohexylhydrazine-1-carbothioamide
by: Md. Azharul Arafath, et al.
Published: (2018-10-01)

Palladium-Catalyzed Amination of Dichloroquinolines with Adamantane-Containing Amines
by: Irina P. Beletskaya, et al.
Published: (2013-02-01)

Quantitative analysis of weak non-covalent interactions in (Z)-3-(4-chlorophenyl)-2-phenylacrylonitrile: insights from PIXEL and Hirshfeld surface analysis
by: Mani Udayakumar, et al.
Published: (2019-04-01)

Quinine Esters with 1,2-Azole, Pyridine and Adamantane Fragments
by: Gulim K. Mukusheva, et al.
Published: (2022-05-01)

Synthesis and Structural Properties of Adamantane‐Substituted Amines and Amides Containing an Additional Adamantane, Azaadamantane or Diamantane Moiety
by: Maxime Bonsir, et al.
Published: (2022-10-01)

QSAR of Reaction Between Hydrazine and Its Derivatives With Nitrous Acid
by: NIE Jiang, et al.
Published: (2022-04-01)

2-[(1E)-[(Z)-2-({[(1Z)-[(E)-2-[(2-Hydroxyphenyl)methylidene]hydrazin-1-ylidene]({[(4-methylphenyl)methyl]sulfanyl})methyl]disulfanyl}({[(4-methylphenyl)methyl]sulfanyl})methylidene)hydrazin-1-ylidene]methyl]phenol: crystal structure, Hirshfeld surface analysis and computational study
by: Georgiana Paulus, et al.
Published: (2020-08-01)

Adamantane Containing Peptidoglycan Fragments Enhance RANTES and IL-6 Production in Lipopolysaccharide-Induced Macrophages
by: Mateja Manček-Keber, et al.
Published: (2020-08-01)

Bis(2-Cyclooctylidenehydrazene-1-carbothioamide)Zinc(II), a good single source precursor for ZnS nanoparticles – Synthesis and crystal structure
by: Jisha George, et al.
Published: (2022-01-01)

Promoting Effect of Cu on Pd Applied to the Hydrazine Electro-Oxidation and Direct Hydrazine Fuel Cells
by: Rudy Crisafulli, et al.
Published: (2022-12-01)

Adamantane-Resistant Influenza Infection During the 2004–05 Season
by: Mahbubur Rahman, et al.
Published: (2008-01-01)

4-Aminoquinoline-Based Adamantanes as Potential Anticholinesterase Agents in Symptomatic Treatment of Alzheimer’s Disease
by: Katarina Komatović, et al.
Published: (2022-06-01)

1,1-Bis(diphenylphosphoryl)hydrazine
by: Martha Höhne, et al.
Published: (2018-05-01)

Derivatives of hydrazine and other hydronitrogens having N-N bonds/
by: 215758 Smith, Peter A.
Published: (1983)