Benefits of resistance training on body composition and glucose clearance are inhibited by long-term low carbohydrate diet in rats.
<h4>Background/objectives</h4>Regular exercise training is effective to altering many markers of metabolic syndrome and its effects are strongly influenced by the type of consumed diet. Nowadays, resistance training (RT) has been frequently associated with low-carbohydrate high-fat diet...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2018-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0207951 |
| _version_ | 1818725489107271680 |
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| author | Uliana Sbeguen Stotzer Graziéle Fernanda Deriggi Pisani Gustavo Henrique Rigo Canevazzi Gilberto Eiji Shiguemoto Ana Cláudia Garcia de Oliveira Duarte Sergio Eduardo de Andrade Perez Heloisa Sobreiro Selistre-de-Araújo |
| author_facet | Uliana Sbeguen Stotzer Graziéle Fernanda Deriggi Pisani Gustavo Henrique Rigo Canevazzi Gilberto Eiji Shiguemoto Ana Cláudia Garcia de Oliveira Duarte Sergio Eduardo de Andrade Perez Heloisa Sobreiro Selistre-de-Araújo |
| author_sort | Uliana Sbeguen Stotzer |
| collection | DOAJ |
| description | <h4>Background/objectives</h4>Regular exercise training is effective to altering many markers of metabolic syndrome and its effects are strongly influenced by the type of consumed diet. Nowadays, resistance training (RT) has been frequently associated with low-carbohydrate high-fat diet (LCD). After long term these diets causes body weight (BW) regain with deleterious effects on body composition and metabolic risk factors. The effects of RT associated with long-term LCD on these parameters remain unexplored. We aimed to investigate the effects of RT when associated with long-term LCD on BW, feed efficiency, body composition, glucose homeostasis, liver parameters and serum biochemical parameters during BW regain period in rats.<h4>Subjects/methods</h4>Male Sprague-Dawley rats were fed with LCD (LC groups) or standard diet (STD) (ST groups). After 10 weeks-diet animals were separated into sedentary (Sed-LC and Sed-ST) and resistance-trained (RT-LC and RT-ST) groups (N = 8/group). RT groups performed an 11-week climbing program on a ladder with progressive load. Dual x-ray absorptiometry, glucose tolerance tests and insulin tolerance tests were performed at weeks 10 and 20. Liver and serum were collected at week 21.<h4>Results</h4>RT reduced feed efficiency, BW gain, liver fat and total and LDL cholesterol, and improved body composition and glucose clearance in animals fed on STD. In those fed with LCD, RT reduced caloric intake, BW regain, liver fat and serum triglycerides levels. However, improvement in body composition was inhibited and bone mineral density and glucose clearance was further impaired in this association.<h4>Conclusions</h4>The LCD nullifies the beneficial effects of RT on body composition, glucose homeostasis and impairs some health parameters. Our results do not support the association of RT with LCD in a long term period. |
| first_indexed | 2024-12-17T21:43:07Z |
| format | Article |
| id | doaj.art-7781a9d9d3ae49bf885b72d8b4bb3e88 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-17T21:43:07Z |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-7781a9d9d3ae49bf885b72d8b4bb3e882022-12-21T21:31:33ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-011312e020795110.1371/journal.pone.0207951Benefits of resistance training on body composition and glucose clearance are inhibited by long-term low carbohydrate diet in rats.Uliana Sbeguen StotzerGraziéle Fernanda Deriggi PisaniGustavo Henrique Rigo CanevazziGilberto Eiji ShiguemotoAna Cláudia Garcia de Oliveira DuarteSergio Eduardo de Andrade PerezHeloisa Sobreiro Selistre-de-Araújo<h4>Background/objectives</h4>Regular exercise training is effective to altering many markers of metabolic syndrome and its effects are strongly influenced by the type of consumed diet. Nowadays, resistance training (RT) has been frequently associated with low-carbohydrate high-fat diet (LCD). After long term these diets causes body weight (BW) regain with deleterious effects on body composition and metabolic risk factors. The effects of RT associated with long-term LCD on these parameters remain unexplored. We aimed to investigate the effects of RT when associated with long-term LCD on BW, feed efficiency, body composition, glucose homeostasis, liver parameters and serum biochemical parameters during BW regain period in rats.<h4>Subjects/methods</h4>Male Sprague-Dawley rats were fed with LCD (LC groups) or standard diet (STD) (ST groups). After 10 weeks-diet animals were separated into sedentary (Sed-LC and Sed-ST) and resistance-trained (RT-LC and RT-ST) groups (N = 8/group). RT groups performed an 11-week climbing program on a ladder with progressive load. Dual x-ray absorptiometry, glucose tolerance tests and insulin tolerance tests were performed at weeks 10 and 20. Liver and serum were collected at week 21.<h4>Results</h4>RT reduced feed efficiency, BW gain, liver fat and total and LDL cholesterol, and improved body composition and glucose clearance in animals fed on STD. In those fed with LCD, RT reduced caloric intake, BW regain, liver fat and serum triglycerides levels. However, improvement in body composition was inhibited and bone mineral density and glucose clearance was further impaired in this association.<h4>Conclusions</h4>The LCD nullifies the beneficial effects of RT on body composition, glucose homeostasis and impairs some health parameters. Our results do not support the association of RT with LCD in a long term period.https://doi.org/10.1371/journal.pone.0207951 |
| spellingShingle | Uliana Sbeguen Stotzer Graziéle Fernanda Deriggi Pisani Gustavo Henrique Rigo Canevazzi Gilberto Eiji Shiguemoto Ana Cláudia Garcia de Oliveira Duarte Sergio Eduardo de Andrade Perez Heloisa Sobreiro Selistre-de-Araújo Benefits of resistance training on body composition and glucose clearance are inhibited by long-term low carbohydrate diet in rats. PLoS ONE |
| title | Benefits of resistance training on body composition and glucose clearance are inhibited by long-term low carbohydrate diet in rats. |
| title_full | Benefits of resistance training on body composition and glucose clearance are inhibited by long-term low carbohydrate diet in rats. |
| title_fullStr | Benefits of resistance training on body composition and glucose clearance are inhibited by long-term low carbohydrate diet in rats. |
| title_full_unstemmed | Benefits of resistance training on body composition and glucose clearance are inhibited by long-term low carbohydrate diet in rats. |
| title_short | Benefits of resistance training on body composition and glucose clearance are inhibited by long-term low carbohydrate diet in rats. |
| title_sort | benefits of resistance training on body composition and glucose clearance are inhibited by long term low carbohydrate diet in rats |
| url | https://doi.org/10.1371/journal.pone.0207951 |
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