Gene expression parallels synaptic excitability and plasticity changes in Alzheimer´s disease

Gene expression parallels synaptic excitability and plasticity changes in Alzheimer´s disease

Alzheimer´s disease (AD) is a neurodegenerative disorder characterized by abnormal accumulation of β-amyloid and tau and synapse dysfunction in memory-related neural circuits. Pathological and functional changes in the medial temporal lobe, a region essential for explicit memory encoding, contribute...

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Bibliographic Details
Main Authors:	Carlos A Saura, Arnaldo eParra-Damas, Lilian eEnríquez-Barreto
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-08-01
Series:	Frontiers in Cellular Neuroscience
Subjects:	Amyloid Gene Expression Regulation Memory Disorders Transcriptome Alzheimer's disease CREB
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00318/full

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