Site-Directed Genome Knockout in Chicken Cell Line and Embryos Can Use CRISPR/Cas Gene Editing Technology

Site-Directed Genome Knockout in Chicken Cell Line and Embryos Can Use CRISPR/Cas Gene Editing Technology

The present study established an efficient genome editing approach for the construction of stable transgenic cell lines of the domestic chicken (Gallus gallus domesticus). Our objectives were to facilitate the breeding of high-yield, high-quality chicken strains, and to investigate gene function in...

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Bibliographic Details
Main Authors: Qisheng Zuo, Yinjie Wang, Shaoze Cheng, Chao Lian, Beibei Tang, Fei Wang, Zhenyu Lu, Yanqing Ji, Ruifeng Zhao, Wenhui Zhang, Kai Jin, Jiuzhou Song, Yani Zhang, Bichun Li
Format: Article
Language:English
Published: Oxford University Press 2016-06-01
Series:G3: Genes, Genomes, Genetics
Subjects:
CRISPR/Cas
chicken
gene knockout
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.028803

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