Clinicopathologic features, genomic profiles and outcomes of younger vs. older Chinese hormone receptor-positive (HR+)/HER2-negative (HER2-) metastatic breast cancer patients

Clinicopathologic features, genomic profiles and outcomes of younger vs. older Chinese hormone receptor-positive (HR+)/HER2-negative (HER2-) metastatic breast cancer patients

BackgroundPoor outcomes have been widely reported for younger vs. older breast cancer patients, but whether this is due to age itself or the enrichment of aggressive clinical features remains controversial. We have evaluated the clinicopathologic characteristics and genomic profiles of real-world ho...

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Bibliographic Details
Main Authors: Jinhao Wang, Yaxin Liu, Yuehua Liang, Yue Zhang, Hang Dong, Tiantian Zheng, Jianjun Yu, Pan Du, Shidong Jia, Bonnie L. King, Jing Wang, Xiaoran Liu, Huiping Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
hormone receptor-positive breast cancer
metastatic breast cancer
cfDNA
liquid biopsy
biomarkers
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1152575/full

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