Evaluation of triglyceride-glucose index, triglyceride to high-density lipoprotein cholesterol ratio, and other lipid ratios in hypertension
Background: Hypertension is one of the most common diseases with increasing morbidity and mortality. HTN is associated with cardiovascular risk factors such as insulin resistance (IR) and hyperlipidemia. Recently, triglyceride-glucose (TyG) index has been proposed as a marker for insulin resistance....
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2023-03-01
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| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/49118 |
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| author | Jyotsna Kiro Madhusmita Acharya Sumitra Bhoi Sanghamitra Bhoi Neelam B Tirkey |
| author_facet | Jyotsna Kiro Madhusmita Acharya Sumitra Bhoi Sanghamitra Bhoi Neelam B Tirkey |
| author_sort | Jyotsna Kiro |
| collection | DOAJ |
| description | Background: Hypertension is one of the most common diseases with increasing morbidity and mortality. HTN is associated with cardiovascular risk factors such as insulin resistance (IR) and hyperlipidemia. Recently, triglyceride-glucose (TyG) index has been proposed as a marker for insulin resistance.
Aims and Objectives: This study aimed to assess TyG index, triglyceride to high-density lipoprotein ratio, and other lipid ratios in HTN patients.
Materials and Methods: The present study was conducted on 200 subjects and was categorized into two groups. 100 hypertensive patients were considered as cases and 100 healthy individuals as controls. Serum sample of the subjects was used for the estimation of total cholesterol, triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C). Low-density lipoprotein (LDL) cholesterol was calculated. TyG index and TG/HDL ratio and other lipid ratios were calculated. Blood pressure (BP) was recorded.
Results: In this, BP, total cholesterol, TG, LDL, Very low-density lipoprotein cholesterol, Non-HDLC, TC/HDL ratio, TG/HDL ratio, and TyG index were increased in cases and HDL and HDL/LDL ratio were decreased. Study parameters were positively correlated with TyG index and TG/HDL ratio, except HDL, and HDL/LDL ratio.
Conclusion: The study concludes that significantly increased TyG index and TG/HDL ratio in hypertensive cases and their correlation with blood pressure. |
| first_indexed | 2024-04-10T06:22:52Z |
| format | Article |
| id | doaj.art-778757ce51c24ff98cee0ed3da80bd66 |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-04-10T06:22:52Z |
| publishDate | 2023-03-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-778757ce51c24ff98cee0ed3da80bd662023-03-02T01:15:07ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762023-03-0114398102https://doi.org/10.3126/ajms.v14i3.49118Evaluation of triglyceride-glucose index, triglyceride to high-density lipoprotein cholesterol ratio, and other lipid ratios in hypertensionJyotsna Kiro0https://orcid.org/0000-0002-0787-4937Madhusmita Acharya 1https://orcid.org/0000-0002-0333-6314Sumitra Bhoi 2https://orcid.org/0000-0003-0490-5408Sanghamitra Bhoi 3https://orcid.org/0000-0001-7559-0955Neelam B Tirkey 4https://orcid.org/0000-0002-8691-7367Assistant Professor, Department of Biochemistry, Veer Surendra Sai Institute of Medical Sciences and Research, Sambalpur, Odisha, India Professor and Head, Department of Biochemistry, Veer Surendra Sai Institute of Medical Sciences and Research, Sambalpur, Odisha, IndiaAssociate Professor, Department of Biochemistry, Veer Surendra Sai Institute of Medical Sciences and Research, Sambalpur, Odisha, India Assistant Professor, Department of Biochemistry, Veer Surendra Sai Institute of Medical Sciences and Research, Sambalpur, Odisha, India Assistant Professor, Department of Biochemistry, Veer Surendra Sai Institute of Medical Sciences and Research, Sambalpur, Odisha, India Background: Hypertension is one of the most common diseases with increasing morbidity and mortality. HTN is associated with cardiovascular risk factors such as insulin resistance (IR) and hyperlipidemia. Recently, triglyceride-glucose (TyG) index has been proposed as a marker for insulin resistance. Aims and Objectives: This study aimed to assess TyG index, triglyceride to high-density lipoprotein ratio, and other lipid ratios in HTN patients. Materials and Methods: The present study was conducted on 200 subjects and was categorized into two groups. 100 hypertensive patients were considered as cases and 100 healthy individuals as controls. Serum sample of the subjects was used for the estimation of total cholesterol, triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C). Low-density lipoprotein (LDL) cholesterol was calculated. TyG index and TG/HDL ratio and other lipid ratios were calculated. Blood pressure (BP) was recorded. Results: In this, BP, total cholesterol, TG, LDL, Very low-density lipoprotein cholesterol, Non-HDLC, TC/HDL ratio, TG/HDL ratio, and TyG index were increased in cases and HDL and HDL/LDL ratio were decreased. Study parameters were positively correlated with TyG index and TG/HDL ratio, except HDL, and HDL/LDL ratio. Conclusion: The study concludes that significantly increased TyG index and TG/HDL ratio in hypertensive cases and their correlation with blood pressure.https://www.nepjol.info/index.php/AJMS/article/view/49118hypertension; triglyceride-glucose index; triglycerides/high-density lipoprotein ratio |
| spellingShingle | Jyotsna Kiro Madhusmita Acharya Sumitra Bhoi Sanghamitra Bhoi Neelam B Tirkey Evaluation of triglyceride-glucose index, triglyceride to high-density lipoprotein cholesterol ratio, and other lipid ratios in hypertension Asian Journal of Medical Sciences hypertension; triglyceride-glucose index; triglycerides/high-density lipoprotein ratio |
| title | Evaluation of triglyceride-glucose index, triglyceride to high-density lipoprotein cholesterol ratio, and other lipid ratios in hypertension |
| title_full | Evaluation of triglyceride-glucose index, triglyceride to high-density lipoprotein cholesterol ratio, and other lipid ratios in hypertension |
| title_fullStr | Evaluation of triglyceride-glucose index, triglyceride to high-density lipoprotein cholesterol ratio, and other lipid ratios in hypertension |
| title_full_unstemmed | Evaluation of triglyceride-glucose index, triglyceride to high-density lipoprotein cholesterol ratio, and other lipid ratios in hypertension |
| title_short | Evaluation of triglyceride-glucose index, triglyceride to high-density lipoprotein cholesterol ratio, and other lipid ratios in hypertension |
| title_sort | evaluation of triglyceride glucose index triglyceride to high density lipoprotein cholesterol ratio and other lipid ratios in hypertension |
| topic | hypertension; triglyceride-glucose index; triglycerides/high-density lipoprotein ratio |
| url | https://www.nepjol.info/index.php/AJMS/article/view/49118 |
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