SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound <i>Sparus aurata</i> Skin
Skin lesions are a frequent fact associated with intensive conditions affecting farmed fish. Knowing that the use of probiotics can improve fish skin health, SpPdp11 dietary administration has demonstrated beneficial effects for farmed fish, so its potential on the skin needs to be studied more deep...
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MDPI AG
2023-01-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/13/2/193 |
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| author | Isabel M. Cerezo Olivia Pérez-Gómez Rocio Bautista Pedro Seoane M. Ángeles Esteban M. Carmen Balebona Miguel A. Moriñigo Silvana T. Tapia-Paniagua |
| author_facet | Isabel M. Cerezo Olivia Pérez-Gómez Rocio Bautista Pedro Seoane M. Ángeles Esteban M. Carmen Balebona Miguel A. Moriñigo Silvana T. Tapia-Paniagua |
| author_sort | Isabel M. Cerezo |
| collection | DOAJ |
| description | Skin lesions are a frequent fact associated with intensive conditions affecting farmed fish. Knowing that the use of probiotics can improve fish skin health, SpPdp11 dietary administration has demonstrated beneficial effects for farmed fish, so its potential on the skin needs to be studied more deeply. The wounded specimens that received the diet with SpPdp11 showed a decrease in the abundance of <i>Enterobacteriaceae</i>, <i>Photobacterium</i> and <i>Achromobacter</i> related to bacterial biofilm formation, as well as the overexpression of genes involved in signaling mechanisms (<i>itpr3</i>), cell migration and differentiation (<i>panxa</i>, <i>ttbk1a</i>, <i>smpd3</i>, <i>vamp5</i>); and repression of genes related to cell proliferation (<i>vstm4a</i>, <i>areg</i>), consistent with a more efficient skin healing processes than that observed in the wounded control group. In addition, among the groups of damaged skin with different diets, <i>Achromobacter</i>, f_<i>Ruminococcaceae</i>, p_<i>Bacteroidetes</i>, <i>Fluviicola</i> and <i>Flavobacterium</i> genera with significant differences showed positive correlations with genes related to cell migration and negative correlations with inflammation and cell proliferation and may be the target of future studies. |
| first_indexed | 2024-03-09T13:49:10Z |
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| language | English |
| last_indexed | 2024-03-09T13:49:10Z |
| publishDate | 2023-01-01 |
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| record_format | Article |
| series | Animals |
| spelling | doaj.art-778a4e9df9304aa7949a72681be7ec622023-11-30T20:52:31ZengMDPI AGAnimals2076-26152023-01-0113219310.3390/ani13020193SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound <i>Sparus aurata</i> SkinIsabel M. Cerezo0Olivia Pérez-Gómez1Rocio Bautista2Pedro Seoane3M. Ángeles Esteban4M. Carmen Balebona5Miguel A. Moriñigo6Silvana T. Tapia-Paniagua7Instituto de Biotecnología y Desarrollo Azul (IBYDA), Faculty of Sciences, Department of Microbiology, University of Malaga, 29010 Málaga, SpainInstituto de Biotecnología y Desarrollo Azul (IBYDA), Faculty of Sciences, Department of Microbiology, University of Malaga, 29010 Málaga, SpainSCBI, Bioinformatic Unit, University of Malaga, 29590 Málaga, SpainFaculty of Sciences, Department of Molecular Biology and Biochemistry, University of Malaga, 29010 Málaga, SpainCampus Regional de Excelencia Internacional “Campus Mare Nostrum”, Faculty of Biology, Department of Cell Biology and Histology, University of Murcia, 30100 Murcia, SpainInstituto de Biotecnología y Desarrollo Azul (IBYDA), Faculty of Sciences, Department of Microbiology, University of Malaga, 29010 Málaga, SpainInstituto de Biotecnología y Desarrollo Azul (IBYDA), Faculty of Sciences, Department of Microbiology, University of Malaga, 29010 Málaga, SpainInstituto de Biotecnología y Desarrollo Azul (IBYDA), Faculty of Sciences, Department of Microbiology, University of Malaga, 29010 Málaga, SpainSkin lesions are a frequent fact associated with intensive conditions affecting farmed fish. Knowing that the use of probiotics can improve fish skin health, SpPdp11 dietary administration has demonstrated beneficial effects for farmed fish, so its potential on the skin needs to be studied more deeply. The wounded specimens that received the diet with SpPdp11 showed a decrease in the abundance of <i>Enterobacteriaceae</i>, <i>Photobacterium</i> and <i>Achromobacter</i> related to bacterial biofilm formation, as well as the overexpression of genes involved in signaling mechanisms (<i>itpr3</i>), cell migration and differentiation (<i>panxa</i>, <i>ttbk1a</i>, <i>smpd3</i>, <i>vamp5</i>); and repression of genes related to cell proliferation (<i>vstm4a</i>, <i>areg</i>), consistent with a more efficient skin healing processes than that observed in the wounded control group. In addition, among the groups of damaged skin with different diets, <i>Achromobacter</i>, f_<i>Ruminococcaceae</i>, p_<i>Bacteroidetes</i>, <i>Fluviicola</i> and <i>Flavobacterium</i> genera with significant differences showed positive correlations with genes related to cell migration and negative correlations with inflammation and cell proliferation and may be the target of future studies.https://www.mdpi.com/2076-2615/13/2/193aquaculturefishgilthead seabreammicrobiotaprobioticRNA seq |
| spellingShingle | Isabel M. Cerezo Olivia Pérez-Gómez Rocio Bautista Pedro Seoane M. Ángeles Esteban M. Carmen Balebona Miguel A. Moriñigo Silvana T. Tapia-Paniagua SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound <i>Sparus aurata</i> Skin Animals aquaculture fish gilthead seabream microbiota probiotic RNA seq |
| title | SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound <i>Sparus aurata</i> Skin |
| title_full | SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound <i>Sparus aurata</i> Skin |
| title_fullStr | SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound <i>Sparus aurata</i> Skin |
| title_full_unstemmed | SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound <i>Sparus aurata</i> Skin |
| title_short | SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound <i>Sparus aurata</i> Skin |
| title_sort | sppdp11 administration in diet modified the transcriptomic response and its microbiota associated in mechanically induced wound i sparus aurata i skin |
| topic | aquaculture fish gilthead seabream microbiota probiotic RNA seq |
| url | https://www.mdpi.com/2076-2615/13/2/193 |
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