Structural genomics approach to investigate deleterious impact of nsSNPs in conserved telomere maintenance component 1

Structural genomics approach to investigate deleterious impact of nsSNPs in conserved telomere maintenance component 1

Abstract Conserved telomere maintenance component 1 (CTC1) is an important component of the CST (CTC1-STN1-TEN1) complex, involved in maintaining the stability of telomeric DNA. Several non-synonymous single-nucleotide polymorphisms (nsSNPs) in CTC1 have been reported to cause Coats plus syndrome an...

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Bibliographic Details
Main Authors:	Arunabh Choudhury, Taj Mohammad, Nikhil Samarth, Afzal Hussain, Md. Tabish Rehman, Asimul Islam, Mohamed F. Alajmi, Shailza Singh, Md. Imtaiyaz Hassan
Format:	Article
Language:	English
Published:	Nature Portfolio 2021-05-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-021-89450-7

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