High-throughput tuning of ovarian cancer spheroids for on-chip invasion assays

High-throughput tuning of ovarian cancer spheroids for on-chip invasion assays

We developed an invasion assay by using microfabricated culture devices. First, ovarian tumor spheroids were generated with a culture patch device consisting of an agarose membrane formed with a honeycomb microframe – the patch – and gelatin nanofiber backbone. By changing the dimensions of the hone...

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Bibliographic Details
Main Authors: Changchong Chen, Yong He, Elliot Lopez, Franck Carreiras, Ayako Yamada, Marie-Claire Schanne-Klein, Ambroise Lambert, Yong Chen, Carole Aimé
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Micro and Nano Engineering
Subjects:
Tumor spheroid
Epithelial-to-mesenchymal transition
Culture substrate
Microfluidics
Online Access:http://www.sciencedirect.com/science/article/pii/S2590007222000351

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